COVID-19 Updates

Visit UC San Diego's Coronavirus portal for the latest information for the campus community.

Publications

Names of current and past lab members are underlined and bolded. Free articles are linked in the titles.

Published Articles in Peer Reviewed Journals Arranged by Topic

Epicatechin's effect on skeletal muscle and mitochondrial function

  1. Yamazaki KG, Taub PR, Barraza-Hidalgo M, Rivas MM, Zambon AC, Ceballos G, Villarreal FJ. Effects of (-)-epicatechin on myocardial infarct size and left ventricular remodeling after permanent coronary occlusion. J Am Coll Cardiol. 2010;55(25):2869-76 (PMID 20579545, PMC2915587).
  2. Nogueira L, Ramirez-Sanchez I, Perkins GA, Murphy A, Taub PR, Ceballos G, Villarreal FJ, Hogan MC, Malek MH. (-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle. J Physiol. 2011;589(Pt 18):4615-31 (PMID 21788351, PMC3208228).
  3. Taub PR, Ramirez-Sanchez I, Ciaraldi TP, Perkins G, Murphy AN, Naviaux R, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F. Alterations in skeletal muscle indicators of mitochondrial structure and biogenesis in patients with type 2 diabetes and heart failure: effects of epicatechin rich cocoa. Clin Transl Sci. 2012;5(1):43-7 (PMID 22376256, PMC5439909).
  4. Ramirez-Sanchez I, Nogueira L, Morena A, Murphy A, Taub PR, Perkins G, Ceballos G, Hogan M, Malek MH, Villarreal F. Perturbations in skeletal muscle sarcomere structure in patients with heart failure and type 2 diabetes: restorative effects of (-)-epicatechin-rich cocoa. J Cardiovasc Pharmacol. 2012;60:429-38 (PMID 22833114, PMC3496054)
  5. Ramirez-Sanchez I, Taub PR, Ciaraldi TP, Nogueira L, Coe T, Perkins G, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F. (-)-Epicatechin rich cocoa mediated modulation of oxidative stress regulators in skeletal muscle of heart failure and type 2 diabetes patients. Int J Cardiol. 2013;168(4):3982-90 (PMID 23870648, PMC3805662).
  6. Taub PR, Ramirez-Sanchez I, Ciaraldi T, Gonzalez-Basurto S, Coral-Vazquez R, Perkins G, Hogan M, Maisel A, Henry R, Ceballos G, Villarreal F. Severe perturbations in skeletal muscle sarcomere structure of heart failure and type 2 diabetes patients: Restorative effects of (-)-epicatechin-rich cocoa. Clin Sci. 2013;125:383-89 (PMID 23642227, PMC3805662).
  7. Gutierrez-Salmean G, Ciaraldi T, Nogueira L, Taub PR, Hogan M, Henry R, Meany E, Villarreal F, Ceballos G, Ramirez-Sanchez I. Effects of (-)-epicatechin on molecular modulators of skeletal muscle growth and differentiation. J Nut Biochem. 2013;25:91-4 (PMID 2431487, PMC3857584).
  8. Ortiz-Vilchis P, Yamazaki KG, Rubio-Gayosso I, Ramirez-Sanchez I, Calzada C, Romero-Perez D, Ortiz A, Meaney E, Taub PR, Villarreal F, Ceballos G. Co-administration of the flavanol (-)-epicatechin with doxycycline synergistically reduces infarct size in a model of ischemia reperfusion injury by inhibition of mitochondrial swelling. Eur J Pharmacol. 2014;744:76-82 (PMID 25281837, PMC5109834).
  9. Barnett CF, Moreno-Ulloa A, Shiva S, Ramirez-Sanchez I, Taub PR, Su Y, Ceballos G, Dugar S, Schreiner G, Villarreal F. Pharmacokinetic, partial pharmacodynamics and initial safety analysis of (-)-epicatechin in healthy volunteers. Food Funct. 2015;6(3):824-33 (PMID 25598082, PMC4357542).
  10. Taub PR, Ramirez-Sanchez I, Patel M, Higginbotham E, Moreno-Ulloa A, Roman L, Phillips P, Ceballos G, Villareal F.  Beneficial effects of dark chocolate on exercise capacity in sedentary subjects: Underlying mechanisms. A double blind, randomized, placebo-controlled trial.  Food Funct. 2016;7(9):3686-93. (PMID 27491778, PMC5025384).
  11. Gutierrez-Salmean G, Meany E, Lanaspa MA, Cicerchi C, Johnson RJ, Dugar S, Taub PR, Ramirez-Sanchez I, Villarreal F, Schreiner G, Ceballos G. A randomized, placebo-controlled, double-blind study on the effects of (-)-epicatechin on the triglyceride/HDLc ratio and cardiometabolic profile of subjects with hypertriglyceridemia: unique in vitro effects. Int J Cardiol. 2016; 223:500-506 (PMID 27552564).
  12. Formentini L, Ryan AJ, Gálvez-Santisteban M, Carter L, Taub P, Lapek JD Jr, Gonzalez DJ, Villarreal F, Ciaraldi TP, Cuezva JM, Henry RR.  Mitochondrial H+-ATP synthase in human skeletal muscle: contribution to dyslipidaemia and insulin resistance.  Diabetologia. 2017;60(10):2052-2065 (PMID 28770317, PMC6572787).
  13. Moreno-Ulloa A, Nájera-García N, Hernández M, Ramírez-Sánchez I, Taub PR, Su Y, Beltrán-Partida E, Ceballos G, Dugar S, Schreiner G, Best BM, Ciaraldi TP, Henry RR, Villarreal F. A pilot study on clinical pharmacokinetics and preclinical pharmacodynamics of (+)-epicatechin on cardiometabolic endpoints. Food Funct. 2018;9(1):307-319 (PMID 29171848, PMC5783763).

Cardiometabolic Effects of Time-Restricted Eating

  1. Sulli G, Manoogian ENC, Taub PR, Panda S. Training the Circadian Clock, Clocking the Drugs, and Drugging the Clock to Prevent, Manage, and Treat Chronic Diseases. Trends Pharmacol Sci. 2018:pii: S0165-6147(18)30119-6 (PMID 30060890).
  2. Wilkinson MJ, Manoogian ENC, Zadourian A, Lo HC, Fakhouri S, Shoghi A, Wang X, Fleischer JG, Navlakha S, Panda S, Taub PR. Ten-hour time-restricted eating reduces weight, blood pressure, and atherogenic lipids in patients with metabolic syndrome. Cell Metab. 2019. [Epub ahead of print].

Biomarkers

  1. Ko N, Rajendran PR, Kim H, Rutowski M, Pawlikowska L, Kowk P, Higashida R, Lawton M, Smith W, Zaroff J, Young W. Endothelial nitric oxide synthase polymorphism and risk of cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Stroke. 2008;39(4):1103-8 (PMID 18309169, PMC2650384).
  2. Taub PR, Daniels LB, Maisel AS. Usefulness of B-type natriuretic peptide levels in predicting hemodynamic and clinical decompensation. Heart Fail Clin. 2009;5(2):169-75 (PMID 19249686).
  3. Taub PR, Gabbai-Saldate P, Maisel A. Biomarkers of heart failure. Congest Heart Fail. 2010;16 Suppl 1:S19-24 (PMID 20653707).
  4. Taub PR, Fields J, Wu AH, Miss J, Lawton M, Smith WS, Young WL, Zaroff JG, Ko NU. Elevated BNP is Associated with vasospasm-independent cerebral infarction following aneurysmal subarachnoid hemorrhage. Neurocritical Care 2011;15:13-18. (PMID 21479679, PMC3133817).
  5. Xue Y, Taub PR, Fard A, Maisel AS. Hypervolemic and optivolemic natriuretic peptides in acute heart failure. Contrib Nephrol 2011;171:74-9. (PMID 21625093).
  6. Xue Y, Taub PR, Iqbal N, Fard A, Wentworth B, Redwine L, Clopton P, Stein M, Maisel A. Cardiac biomarkers, mortality, and post-traumatic stress disorder in military veterans. Am J Cardiol. 2012;109(8):1215-8 (PMID 22305506).
  7. Taub PR, Borden KC, Fard A, Maisel A. Role of biomarkers in the diagnosis and prognosis of acute kidney injury in patients with cardiorenal syndrome. Expert Rev Cardiovasc Ther. 2012;10(5):657-67 (PMID 22651841, PMC4060800).
  8. Prasain JK, Arabshahi A, Taub PR, Sweeney S, Moore R, Sharer JD, Barnes S. Simultaneous quantification of F2-isoprostanes and prostaglandins in human urine by liquid chromatography tandem-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2013;913-914:161-8 (PMID 23314354, PMC3779072).
  9. Wentworth BA, Stein MB, Redwine LS, Xue Y, Taub PR, Clopton P, Nayak KR, Maisel AS. Post-traumatic stress disorder: a fast track to premature cardiovascular disease? Cardiol Rev. 2013;21(1):16-22 (PMID 22717656).
  10. Xue Y*, Taub PR*, Iqbal N, Fard A, Clopton P, Maisel A. Mid-region pro-adrenomedullin adds predictive value to clinical predictors and Framingham risk score for long-term mortality in stable outpatients with heart failure.  Eur J Heart Fail 2013;15:1343-9 (PMID 23887059). *co-first author
  11. Maisel A, Barnard D, Jaski B, Frivold G, Marais J, Azer M, Miyamoto MI, Lombardo D, Kelsay D, Borden K, Iqbal N, Taub PR, Kupfer K, Clopton P, Greenberg B. Primary results of the HABIT Trial (heart failure assessment with BNP in the home). J Am Coll Cardiol. 2013;61(16):1726-35 (PMID 23500322).
  12. Tokman S, Barnett CF, Jarlsberg LG, Taub PR, den Boon S, Davis JL, Cattamanchi A, Worodria W, Maisel A, Huang L. International HIV-Associated Opportunistic Pneumonias (IHOP) Study Group. Procalcitonin predicts mortality in HIV-infected Ugandan adults with lower respiratory tract infections. Respirology. 2014 Apr;19(3):382-8  (PMID 24460728, PMC4276722).
  13. Shah KS, Taub PR, Patel M, Rehfeldt M, Struck J, Clopton P, Mehta RL, Maisel AS. Proenkephalin predicts acute kidney injury in cardiac surgery patients. Clin Nephrol. 2015;83(1):29-35 (PMID 25512100).
  14. Maisel AS, Shah KS, Barnard D, Jaski B, Frivold G, Marais J, Azer M, Miyamoto MI, Lombardo D, Kelsay D, Iqbal N, Taub PR, Kupfer K, Lee E, Clopton P, Zile M, Greenberg B. How B-Type Natriuretic Peptide (BNP) and Body Weight Changes Vary in Heart Failure With Preserved Ejection Fraction Compared With Reduced Ejection Fraction: Secondary Results of the HABIT (HF Assessment With BNP in the Home) Trial. J Card Fail. 2016;22(4):283-93. (PMID 26433086)
  15. Maisel AS, Wettersten N, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müller GA, Birkhahn R, Clopton P, Taub P, Vilke GM, McDonald K, Mahon N, Nuñez J, Briguori C, Passino C, Murray PT. Neutrophil Gelatinase-Associated Lipocalin for Acute Kidney Injury During Acute Heart Failure Hospitalizations: The AKINESIS Study. J Am Coll Cardiol. 2016; 68(13):1420-31 (PMID 27659464).
  16. Murray PT, Wettersten N, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müeller GA, Birkhahn R, Horiuchi Y, Clopton P, Taub P, Vilke GM, Barnett O, McDonald K, Mahon N, Nuñez J, Briguori C, Passino C, Maisel A. Utility of Urine Neutrophil Gelatinase-Associated Lipocalin for Worsening Renal Function during Hospitalization for Acute Heart Failure: Primary findings for urine N-gal Acute Kidney Injury N-gal Evaluation of Symptomatic heart faIlure Study (AKINESIS). J Card Fail. 2019;25(8):654-665 (PMID: 31128242).
  17. Wettersten N, Horiuchi Y, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müeller GA, Birkhahn R, Taub PR, Vilke GM, Barnett O, McDonald K, Mahon N, Nuñez J, Briguori C, Passino C, Maisel A, Murray PT. Short-term prognostic implications of serum and urine neutrophil gelatinase-associated lipocalin in acute heart failure: findings from the AKINESIS study. Eur J Heart Fail. 2020 Feb;22(2):251-263 (PMID: 31863682).
  18. Świątkiewicz I, Magielski P, Kubica J, Zadourian A, DeMaria AN, Taub PR. Enhanced Inflammation is a Marker for Risk of Post-Infarct Ventricular Dysfunction and Heart Failure. Int J Mol Sci. 2020;21(3):807 (PMID: 31991903; PMCID: PMC7037521).
  19. Dong TA, Sandesara PB, Dhindsa DS, Mehta A, Arneson LC, Dollar AL, Taub PR, Sperling LS. Intermittent Fasting: A Heart Healthy Dietary Pattern? Am J Med. 2020;21(4). (PMID: 3233049).                                   [Epub ahead of print]

Other Publications in Chronological Order

  1. Hersh BP, Rajendran PR, Battinelli D, Parkinsomism as the presenting manifestation of HIV infection: improvement on HAART. Neurology. 2001;56:278-9 (PMID: 11160977).
  2. Rajendran PR. The internet: ushering in a new era of medicine. JAMA. 2001;285:804 (PMID 11176920).
  3. Rajendran PR, Thompson RE, Reich SG. The use of alternative therapies by patients with Parkinson's disease. Neurology. 2001;57:790-4 (PMID: 11552005).
  4. Rajendran PR. Ethical issues involved in disclosing medical errors. JAMA. 2001;286(9):1078 (PMID 11559295).
  5. Rajendran PR, Molitor J. Resolution of hypertensive encephalopathy and scleroderma renal crisis with an angiotensin receptor blocker. J Clin Rheumatol. 2005;11:205-8 (PMID 16357757).
  6. Yarlagadda S. Rajendran PR, Miss J, Banki N, Kopelnik A, Ko N, Gelb A, Lawton M, Smith W, Young W, Zaroff J. Cardiovascular predictors of inpatient mortality after subarachnoid hemorrhage. Neurocrit Care. 2006;5(2):102-7 (PMID 17099255).
  7. Taub PR, Higginbotham E, Henry RR. Beneficial and detrimental effects of glycemic control on cardiovascular disease in type 2 diabetes. Current Cardiology Reports. 2013:2:332 (PMID 23314689).
  8. Higginbotham ETaub PR.  Cardiovascular benefits of dark chocolate?  Curr Treat Options Cardiovasc Med. 2015;(12):54 (PMID 26456559).
  9. Aggarwal M, Devries S, Freeman AM, Ostfeld R, Gaggin H, Taub P, Rzeszut AK, Allen K, Conti RC. The Deficit of Nutrition Education of Physicians. Am J Med. 2018;131(4):339-345 (PMID 29269228).
  10. Swiatkiewicz I, Taub PR. The usefulness of C-reactive protein for the prediction of post-infarct left ventricular systolic dysfunction and heart failure. Kardiol Pol. 2018;76(5):821-829 (PMID 29633232).
  11. Zadourian A, Doherty TA, Swiatkiewicz I, and Taub PR. Postural Orthostatic Tachycardia Syndrome: Prevalence, Pathophysiology, and Management. Drugs. 2018; 78(10):983-994 (PMID 29943373).
  12. Henry RR, Müller-Wieland D, Taub PR, Bujas-Bobanovic M, Louie MJ, Letierce A, Ginsberg HN. Effect of alirocumab on lipids and lipoproteins in individuals with metabolic syndrome without diabetes: Pooled data from 10 phase 3 trials. Diabetes Obes Metab. 2018;20(7):1632-1641 (PMID 29493859).
  13. Freeman AM, Taub PR, Lo HC, Ornish D. Intensive Cardiac Rehabilitation: an Underutilized Resource. Curr Cardiol Rep. 2019;21(4):19 (PMID 30828747).
  14. Modestino AE, Skowronski EA, Pruitt C, Taub PR, Herbst K, Schmid-Schönbein GW, Heller MJ, Mills PJ. Elevated Resting and Postprandial Digestive Proteolytic Activity in Peripheral Blood of Individuals With Type-2 Diabetes Mellitus, With Uncontrolled Cleavage of Insulin Receptors. J Am Coll Nutr. 2019; 38(6):485-492 (PMID: 30964398).
  15. Mills PJ, Taub PR, Lunde O, Pung MA, Wilson K, Pruitt C, Rutledge T, Maisel A, Greenberg BH. Depressive symptoms in asymptomatic stage B heart failure with Type II diabetic mellitus. Clin Cardiol. 2019;42(6):637-643 (PMID: 31017303, PMC6553353).
  16. Sands BE, Taub PR, Armuzzi A, Friedman GS, Moscariello M, Lawendy N, Pedersen RD, Chan G, Nduaka CI, Quirk D, Salese L, Su C, Feagan BG. Tofacitinib Treatment is Associated with Modest and Reversible Increases in Serum Lipids in Patients with Ulcerative Colitis. Clin Gastroenterol Hepatol. 2019; pii: S1542-3565(19)30491-4 (PMID: 31077827).
  17. Murray PT, Wettersten N, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müeller GA, Birkhahn R, Horiuchi Y, Clopton P, Taub P, Vilke GM, Barnett O, McDonald K, Mahon N, Nuñez J, Briguori C, Passino C, Maisel A. Utility of Urine Neutrophil Gelatinase-Associated Lipocalin for Worsening Renal Function during Hospitalization for Acute Heart Failure: Primary findings for urine N-gal Acute Kidney Injury N-gal Evaluation of Symptomatic heart faIlure Study (AKINESIS). J Card Fail. 2019;25(8):654-665 (PMID: 31128242).
  18. Wilkinson MJ, Zadourian A, Taub PRHeart Failure and Diabetes Mellitus: Defining the Problem and Exploring the Interrelationship. Am J Card. 2019; 124(1):S3-S11.

Book Chapters

  1. Kevin Shah, Pam R. Taub, Alan Maisel (2011).  Biomarkers in acute heart failure.  In: Tubaro M, Danchin N, Filippatos G, Goldstein P, Vranckx P, Zahger D, eds.  European Society of Cardiology Textbook of Intensive and Acute Cardiac Care (pp. 335-245).  Oxford: Oxford University Press.
  2. Kabir Singh, Pam R. Taub, Alan Maisel (2011).  Biomarkers.  In: Baliga R (Ed), Cardiology Review (pp. 26-36).   New York: McGraw Hill.

For a complete list of published works by Dr. Pam Taub in My Bibliography, please click here.