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Health Assessment and Instrumentation

HSRC offers expertise in:

  • Measurement Design and Validation
  • Creation, Selection and Validation of Patient Reported Outcomes (PROs) 
  • Content, Construct and Structural Validation of Patient Reported Outcomes (PROs) 
  • Scaling and Scoring Algorithms 
  • Responsiveness Testing and Clinically Important Differences 
  • Validation in New Clinical Populations  
  • Linguistic/Cultural Validation  
  • Literature and Instrument Reviews

Several validated measurement instruments developed by HSRC researchers are widely used to study physical and mental health outcomes.


One of the criticisms of the original, interview driven QWB is that it is more expensive and difficult to administer than competing measures, such as the SF-36. The original QWB is relatively long and complex because it has some branching and probe questions and requires a trained interviewer. We developed a self-administered QWB; referred to as the Quality of Well-Being scale, Self-Administered (QWB-SA) that addresses some of these issues (Kaplan, Ganiats, and Sieber, 1996).

The particular strengths of the QWB-SA are:

  • It includes assessment of symptoms in addition to various areas of functioning.
  • The expanded list of symptoms now includes additional mental health items.
  • To reduce recall bias, the QWB-SA assesses only the 3 days prior to completion of the questionnaire.
  • The scoring of the instrument utilizes population-derived preference weights.

Use of the QWB-SA is growing rapidly. HSRC is conducting a strong and diverse research program toward establishing the psychometric properties of this new measure. Current studies are addressing the ability of the QWB-SA to detect changes in samples of migraineurs, cataract surgery patients, people with severe mental illness, and arthritis patients, as well as validating the sensitivity of this measure translated in Spanish, German, Italian, Swedish, French-Canadian, and Dutch.

To learn more about the QWB-SA, visit:

Contact Information:
For specific questions regarding the QWB-SA, contact:

QWB-Mental Health


Gout Impact Scale


Community Services and Supports (CSS) Tracking, Monitoring, and Evaluation System Project

Prevention and Early Intervention (PEI)

San Diego County Behavioral Health Services

Development of a Translational Tool to Study Yoga Therapy (EPYQ)

Global Consortium for Drug-resistant TB Diagnostics (GCDD)
Diabetes Prevention Program Outcomes Study (DPPOS)

Veterans Telemedicine Studies (VTOPS & DOD)

Integrated Care Model for Improving HCV Outcomes (HCV)