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Publications

Selected publications:

2019

Botulinum toxin blocks mast cells and prevents rosacea like inflammation. Choi JE, Werbel T, Wang Z, Wu CC, Yaksh TL, Di Nardo A. J Dermatol

2017

Skin microbiome and mast cells. Igawa S, Di Nardo A. J Invest Dermatol

TRPV4 Mediates Mast Cell Activation in Cathelicidin-Induced Rosacea Inflammation. Mascarenhas NL, Wang Z, Chang YL, Di Nardo A. J Invest Dermatol

Skin microbiome promotes mast cell maturation by triggering stem cell factor production in keratinocytes. Wang Z, Mascarenhas N, Eckmann L, Miyamoto Y, Sun X, Kawakami T, Di Nardo A. J

2014

Mast cells are key mediators of cathelicidin-initiated skin inflammation in rosacea. Muto Y, Wang Z, Vanderberghe M, Two A, Gallo RL, Di Nardo A J Invest Dermatol Allergy Clin Immunol

Skin mast cells protect mice against vaccinia virus by triggering mast cell receptor S1PR2 and releasing antimicrobial peptides. Wang Z, Lai Y, Bernard JJ, Macleod DT, Cogen AL, Moss B, Di Nardo A J Immunol

2010

Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons. Gregorio J, Meller S, Conrad C, Di Nardo A, Homey B, Lauerma A, Arai N, Gallo RL, Digiovanni J, Gilliet M J Exp Med

Immunotherapy for melanoma: current status and perspectives. Alexandrescu DT, Ichim TE, Riordan NH, Marincola FM, Di Nardo A, Kabigting FD, Dasanu CA J Immunother

Activation of TLR2 by a small molecule produced by Staphylococcus epidermidis increases antimicrobial defense against bacterial skin infections. Lai Y, Cogen AL, Radek KA, Park HJ, Macleod DT, Leichtle A, Ryan AF, Di Nardo A, Gallo RL J Invest Dermatol

2009

Commensal bacteria regulate Toll-like receptor 3-dependent inflammation after skin injury. Lai Y, Di Nardo A, Nakatsuji T, Leichtle A, Yang Y, Cogen AL, Wu ZR, Hooper LV, Schmidt RR, von Aulock S, Radek KA, Huang CM, Ryan AF, Gallo RL Nat Med

Collagen synthesis is suppressed in dermal fibroblasts by the human antimicrobial peptide LL-37. Park HJ, Cho DH, Kim HJ, Lee JY, Cho BK, Bang SI, Song SY, Yamasaki K, Di Nardo A, Gallo RL J Invest Dermatol

2008

Mast cell cathelicidin antimicrobial peptide prevents invasive group A Streptococcus infection of the skin. Di Nardo A, Yamasaki K, Dorschner RA, Lai Y, Gallo RL J Immunol

2007

Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea. Yamasaki K, Di Nardo A, Bardan A, Murakami M, Ohtake T, Coda A, Dorschner RA, Bonnart C, Descargues P, Hovnanian A, Morhenn VB, Gallo RL Nat Med

Recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on toll-like receptor 4, cd44, and md-2. Taylor KR, Yamasaki K, Radek KA, Di Nardo A, Goodarzi H, Golenbock D, Beutler B, Gallo RL Journal of Biological Chemistry

Cathelicidin antimicrobial peptides block dendritic cell TLR4 activation and allergic contact sensitization. Di Nardo A, Braff MH, Taylor KR, Na C, Granstein RD, McInturff JE, Krutzik S, Modlin RL, Gallo RL J Immunol

2005

Augmentation of cutaneous immune responses by ATP gamma S: purinergic agonists define a novel class of immunologic adjuvants. Granstein RD, Ding W, Huang J, Holzer A, Gallo RL, Di Nardo A, Wagner JA J Immunol

Structure-function relationships among human cathelicidin peptides: dissociation of antimicrobial properties from host immunostimulatory activities. Braff MH, Hawkins MA, Di Nardo A, Lopez-Garcia B, Howell MD, Wong C, Lin K, Streib JE, Dorschner R, Leung DY, Gallo RL J Immunol

Keratinocytes store the antimicrobial peptide cathelicidin in lamellar bodies. Braff MH, Di Nardo A, Gallo RL J Invest Dermatol

2003

Cutting edge: mast cell antimicrobial activity is mediated by expression of cathelicidin antimicrobial peptide. Di Nardo A, Vitiello A, Gallo RL J Immunol