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Charles Jaffe, MD, PhD

CEO, Health Level Seven, Inc.


  • Health Level Seven, Inc., Chief Executive Officer, 2007-present
  • Intel Corporation, Santa Clara, CA, Senior Global Strategist, Digital Health Group 2005-07
  • SAIC, La Jolla, CA, Vice President Life Sciences, 2004-5
  • AstraZeneca Pharmaceuticals LP, Wilmington, DE, Director of Medical Informatics, 2000-2004
  • InforMed, Inc., Del Mar, CA, President, 1995-2000
  • San Diego Clinical Research, San Diego, CA, Vice President, Biotechnology, 1993-98
  • Scripps Health, San Diego, CA, Department of Medicine, 1985-2000


  • Integrating the Healthcare Enterprise (IHE), International Board of Directors, 2008-present
  • Biomedical Research Integrated Domain Group (BRIDG), Board of Directors, 2008-present
  • LSIT (Life Sciences) Global Institute, Board of Directors, 2008-present
  • Open Health Tooling Collaborative, Board of Directors, 2007-present
  • Markle Foundation, Connecting for Health, Steering Committee, 2004-present
  • Clinical Data Interchange Standards Consortium (CDISC), Board of Directors and Chair, Scientific Committee, 2001-07
  • Clinical Research Information Exchange (CRiX), National Institutes of Health/National Cancer Institute, Steering Committee, 2005-present
  • Cancer Bioinformatics Grid, National Institutes of Health/National Cancer Institute, Steering Committee, 2004-present
  • American Medical Informatics Association, Chair, Clinical Information Systems WG, 1997-2002, Chair, Professional Relations, 2002-4.
  • Global Trial Bank, Clinical Trial Registry, Steering Committee, 2004-06 and Chair, 2006
  • Swiss Institute of Biotechnology, Board of Directors, 2006-07
  • Drug Information Association, Chair, Electronic Clinical Trials SIAC, 2002-06
  • Heath Information Management Systems Society, Advisory Board, HIMSS Committee on Certification for the EHR, 2004-5 and Principal Investigator, Longitudinal study of the impact of technology for the reduction of medical errors, 2002-03
  • FasterCures, Steering Committee for Clinical Research Integration, 2004-06
  • Aetna-CHAMPUS, Advisory Board, 1992-97
  • BioMed Institution Review Board, Chair, 1994-97


  • Professor, Department of Engineering, Penn State University, Great Valley, 2004-07
  • Assistant Clinical Professor, Department of Medicine, UCSD, 1987-96
  • Attending Physician, Department of Medicine, Scripps Health System, La Jolla, 1987-2000
  • Vice President, Biotechnology, San Diego Clinical Research, 1993-98
  • Director, Clinical Trials, Allergy & Immunology MG, 1991-2000
  • Western Regional Director, National Committee Program, Johns Hopkins University, 1995-8
  • Biosilico, Elsevier, Editor, 2003-2007


  • Johns Hopkins University, Baltimore, MD, BA, 1967
  • Duke University, Durham, NC, MD, 1971
  • Duke University, Durham, NC, PhD 1972


  • Experimental Pathology Fellow, University of Kentucky, Lexington, KY, 1970-71
  • Medical Intern & Resident, Duke University Medical Center, Durham, NC, 1971-73
  • Allergy & Clinical Immunology Fellow, National Institute of Allergy & Infectious Diseases, NIH, Bethesda, MD, 1973-76
  • Hematology Fellow, Georgetown University, Washington, DC, 1976-77


  • Phi Beta Kappa, Johns Hopkins University, 1966
  • Alpha Omega Alpha, Duke University Medical School, 1971
  • National Institutes of Health Medical Scientist, 1967-71
  • American Academy of Allergy & Clinical Immunology Clinical Fellow, 1971
  • WHO Clinical Medicine Award, 1978
  • University of California Distinguished Faculty Award, 1981
  • Institutional Review Board Distinguished Service Award, 1990
  • NIH/National Library of Medicine, Medical Informatics Grantee, 1997
  • American College of Medical Informatics, Fellow, 2003
  • Penn State University, Distinguished Faculty Award, 2006
  • Editor, Biosilico, Elsevier LLC, London, 2002-6
  • Fellow, American College of Medical Informatics, 2003
  • Fellow, American College of Physicians, 2008
  • Fellow, Royal Society of Medicine, 2008


  • American Board of Internal Medicine, Certified, 1975
  • American Board of Allergy & Clinical Immunology, Certified, 1979