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The term "epigenome" refers to the collection of chemical modifications to the DNA and chromatin in the nucleus of a cell, which profoundly influence the functional output of the genome. Epigenome research can provide novel insights into many long-standing questions pertaining to gene regulation and genome function and has the potential to significantly improve our knowledge of human biology and disease.



Our Science

Epigenomics can provide novel insights into many long-standing questions about gene regulation and genome function and can significantly improve our understanding of human biology and disease. Together, this knowledge can lead to breakthrough diagnostic and therapeutic opportunities.

Our mission is to make transformative discoveries which advance science and human health, by applying cutting-edge epigenomic technologies to critical research questions. Learn more...


Our Technology

To make the transformative discoveries that bring us closer to understanding the epigenome in each cell, disease, and individual - we employ state-of-the-art automated platforms for high-throughput epigenomics and single-cell genomics. These platforms enable comprehensive investigation into diverse aspects of the epigenome - and ensure accuracy, reproducibility, and scalability when making these important discoveries. Learn more...


Collaboration

A core part of our mission is to unlock the transformative potential of epigenomics through collaboration. Collaborations with academic and industry partners have the potential to transform our knowledge of the human genome, and to change the paradigm of how we diagnose and treat disease. Learn more...

News

9/12/20. Center Research. Our newest preprint, Cardiac Cell Type-Specific Gene Regulatory Programs and Disease Risk Association is on bioRxiv now!

9/04/20. San Diego Chromatin Club. We were so pleased to have Dr. Howard Y. Chang, Standford University, Howard Huges Medical Institute, as our featured speaker.  Please see his talk Personal Regulome Navigation on the Center's YouTube now.

7/09/20. Center Research. Our newest preprint, CTCF Mediates Dosage and Sequence-context-dependent Transcriptional Insulation through Formation of Local Chromatin Domains is on bioRxiv now!

5/19/20. Center Research. Our newest preprints, An Atlas of Gene Regulatory Elements in Adult Mouse Cerebrum and Single nucleus multiomic profiling reveals age-dynamic regulation of host genes associated with SARS-CoV-2 infection are on bioRxiv now!

Address

9500 Gilman Drive
MC 0767 
La Jolla, California 92093 -0653

CMM-East
Room #1056-8 (Offices)
Room #1087-88 (Lab)

Contacts

Email: epigenome@ucsd.edu
Phone: 858-246-2650
Twitter: @CEpigenomics