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The term "epigenome" refers to the collection of chemical modifications to the DNA and chromatin in the nucleus of a cell, which profoundly influence the functional output of the genome. Epigenome research can provide novel insights into many long-standing questions pertaining to gene regulation and genome function and has the potential to significantly improve our knowledge of human biology and disease.



Our Science

Epigenomics can provide novel insights into many long-standing questions about gene regulation and genome function and can significantly improve our understanding of human biology and disease. Together, this knowledge can lead to breakthrough diagnostic and therapeutic opportunities.

Our mission is to make transformative discoveries which advance science and human health, by applying cutting-edge epigenomic technologies to critical research questions. Learn more...


Our Technology

To make the transformative discoveries that bring us closer to understanding the epigenome in each cell, disease, and individual - we employ state-of-the-art automated platforms for high-throughput epigenomics and single-cell genomics. These platforms enable comprehensive investigation into diverse aspects of the epigenome - and ensure accuracy, reproducibility, and scalability when making these important discoveries. Learn more...


Collaboration

A core part of our mission is to unlock the transformative potential of epigenomics through collaboration. Collaborations with academic and industry partners have the potential to transform our knowledge of the human genome, and to change the paradigm of how we diagnose and treat disease. Learn more...

News

8/07/20San Diego Chromatin Club. Our latest virtual Chromatin Club meeting, featuring Dr. Gerald Crabtree, Stanford University,Howard Hughes Medical Institute was anothr success!  Dr. Crabtree's presentation Chromatin Regulation: Mechanistic Insights from Human Genetics and New Techniques may be viewed on the Center's YouTube channel for a limited time.

7/24/20San Diego Chromatin Club. Our virtual Chromatin Club meeting, featuring Dr. Karen Glass, Albany College of Pharmacy and Health Sciences- Vermon Campus, University of Vermont!  

7/10/20. San Diego Chromatin Club. Our virtual Chromatin Club meeting, featuring crowd-favorite Dr. William Greenleaf, Stanford Univeristy!

7/09/20. Center Research. Our newest preprint, CTCF Mediates Dosage and Sequence-context-dependent Transcriptional Insulation through Formation of Local Chromatin Domains is on bioRxiv now!

6/26/20. San Diego Chromatin Club. A fantastic virtual Chromatin Club meeting, featuring Dr. Karolin Luger, University of Colorado Boulder!

6/12/20. San Diego Chromatin Club.  Our virtual Chromatin Club meeting featuring Dr. Steven Henikoff, Fred Hutchinson Cancer Research Center, was another success! 

5/29/20. San Diego Chromatin Club.  Our virtual Chromatin Club meeting featuring our Dr. Bing Ren, UCSD, hit record attendance! 

5/19/20. Center Research. Our newest preprints, An Atlas of Gene Regulatory Elements in Adult Mouse Cerebrum and Single nucleus multiomic profiling reveals age-dynamic regulation of host genes associated with SARS-CoV-2 infection are on bioRxiv now!

Address

9500 Gilman Drive
MC 0767 
La Jolla, California 92093 -0653

CMM-East
Room #1056-8 (Offices)
Room #1087-88 (Lab)

Contacts

Email: epigenome@ucsd.edu
Phone: 858-246-2650
Twitter: @CEpigenomics