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News & Announcements

8/21/2021: Alysson Muotri, PhD, has used chemistry to change skin cells into neurons, which have multiplied to...
8/19/2021: A research team, led by senior authorPradipta Ghosh, MD, professor in the departments of Medicine a...
8/13/2021: An entirely new approach to big data science could erase the declining odds that a drug entering cl...

Upcoming Seminars

"Imaging Single-mRNA Translation Dynamics Live"
Wednesday, September 29, 2021 at 12:00 PM
Tim Stasevich, Ph.D., (Colorado State University College of Natural Sciences)
Hosted by:Eric Bennett
Location:Zoom
SPECIAL JOINT SEMINAR WITH BIOLOGY
For seminar link, please contact smportillo@health.ucsd.edu
"Heterogeneity of the GFP fitness landscape and data-driven protein design"
Wednesday, October 6, 2021 at 12:00 PM
Fyodor Kondrashov, Ph.D., (IST Austria)
Hosted by:Sergey Kryazhimskiy
Location:Zoom
SPECIAL JOINT SEMINAR WITH BIOLOGY
For seminar link, please contact smportillo@health.ucsd.edu
"RNA Modifications in Immunity"
Wednesday, October 13, 2021 at 12:00 PM
Grace Chen, Ph.D., (Yale University School of Medicine)
Hosted by:Gene Yeo
Location:Zoom
SPECIAL JOINT SEMINAR WITH BIOLOGY
For seminar link, please contact smportillo@health.ucsd.edu

Recent Publications

1/4/2021
Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development
Gorkin DU, Barozzi I, Zhao Y, Zhang Y, Huang H, Lee AY, Li B, Chiou J, Wildberg A, Ding B, Zhang B, Wang M, Strattan JS, Davidson JM, Qiu Y, Afzal V, Akiyama JA, Plajzer-Frick I, Novak CS, Kato M, Garvin TH, Pham QT, Harrington AN, Mannion BJ, Lee EA, Fukuda-Yuzawa Y, He Y, Preissl S, Chee S, Han JY, Williams BA, Trout D, Amrhein H, Yang H, Cherry JM, Wang W, Gaulton K, Ecker JR, Shen Y, Dickel DE, Visel A, Pennacchio LA, Ren B
Nature ():
PUBMED ID: 33398137
DOI: 10.1038/s41586-020-03089-4
1/4/2021
ZNF143 mediates CTCF-bound promoter-enhancer loops required for murine hematopoietic stem and progenitor cell function
Zhou Q, Yu M, Tirado-Magallanes R, Li B, Kong L, Guo M, Tan ZH, Lee S, Chai L, Numata A, Benoukraf T, Fullwood MJ, Osato M, Ren B, Tenen DG
Nat Commun12 (1): 43
PUBMED ID: 33397967
DOI: 10.1038/s41467-020-20282-1
1/4/2021
Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation
Kubo N, Ishii H, Xiong X, Bianco S, Meitinger F, Hu R, Hocker JD, Conte M, Gorkin D, Yu M, Li B, Dixon JR, Hu M, Nicodemi M, Zhao H, Ren B
Nat Struct Mol Biol ():
PUBMED ID: 33398174
DOI: 10.1038/s41594-020-00539-5