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8/21/2021: Alysson Muotri, PhD, has used chemistry to change skin cells into neurons, which have multiplied to...
8/19/2021: A research team, led by senior authorPradipta Ghosh, MD, professor in the departments of Medicine a...
8/13/2021: An entirely new approach to big data science could erase the declining odds that a drug entering cl...

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Recent Publications

Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development
Gorkin DU, Barozzi I, Zhao Y, Zhang Y, Huang H, Lee AY, Li B, Chiou J, Wildberg A, Ding B, Zhang B, Wang M, Strattan JS, Davidson JM, Qiu Y, Afzal V, Akiyama JA, Plajzer-Frick I, Novak CS, Kato M, Garvin TH, Pham QT, Harrington AN, Mannion BJ, Lee EA, Fukuda-Yuzawa Y, He Y, Preissl S, Chee S, Han JY, Williams BA, Trout D, Amrhein H, Yang H, Cherry JM, Wang W, Gaulton K, Ecker JR, Shen Y, Dickel DE, Visel A, Pennacchio LA, Ren B
Nature ():
PUBMED ID: 33398137
DOI: 10.1038/s41586-020-03089-4
ZNF143 mediates CTCF-bound promoter-enhancer loops required for murine hematopoietic stem and progenitor cell function
Zhou Q, Yu M, Tirado-Magallanes R, Li B, Kong L, Guo M, Tan ZH, Lee S, Chai L, Numata A, Benoukraf T, Fullwood MJ, Osato M, Ren B, Tenen DG
Nat Commun12 (1): 43
PUBMED ID: 33397967
DOI: 10.1038/s41467-020-20282-1
Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation
Kubo N, Ishii H, Xiong X, Bianco S, Meitinger F, Hu R, Hocker JD, Conte M, Gorkin D, Yu M, Li B, Dixon JR, Hu M, Nicodemi M, Zhao H, Ren B
Nat Struct Mol Biol ():
PUBMED ID: 33398174
DOI: 10.1038/s41594-020-00539-5