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CBIO Training Program Lecture Schedule

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Date Speaker  Lab  Title of Talk 
2020 / 2021
​06/04/21
​Dominic Schenone,
Predoc Trainee
​Heinz Lab
HOXB13 Estrogen Receptor Reprogramming in
HR+ Breast Cancer
​05/07/21
​Alexandra Tankka,
Predoc Trainee
​Yeo Lab
​Identification of microRNA-mRNA gene silencing
interactions required for MYC-driven cancer growth
04/02/21
​Victoria Wu, Predoc Trainee
​Gutkind Lab
​Targeting the Prostaglandin Receptor Gas
Signaling 
Axis as a Novel Immune Checkpoint
of Cytotoxic
T-Cells in Cancer
​03/05/21
​Dan Cunningham-Bryant, Ph.D.
​Ren Lab
​Deciphering Context-Specific Enhancer Function
Using Highly Multiplexed Imaging
02/05/21​
Esther Park, Ph.D.
Rich Lab
​Targeting Cancer-Specific Innatye Immunity with
Zika Virus
01/08/21
​August Williams, Predoc Trainee
​Hangauer Lab
Revealing the Origin of Acquired Drug Resistance
Mutations in Cancer
12/04/20​
​Meghana Pagadala, Predoc
Trainee
​Carter Lab
Germline Variants that Modify Tumor-Immune
Interactions
​11/06/20
​Chris Putnam, Ph.D.
​Assistant Professor, Department of
Medicine
​CRISPR Pickels & Bagel
10/02/20
​Jason Sicklick, MD
​Professor and Executive Vice Chair
of Research, Department of Surgery
​Gastrointestinal Stromal Tumor: Slicing the
Genomic 
Pie and Cutting Through the Tumor
Microenvironment
​09/04/20
​Ed Stites, MD, Ph.D.
​Assitant Professor, Hearst Foundation
Developmental Chair, Salk Institute for 
Biological Sciences
​Understanding Your Data and How it is Analyzed
​2019 / 2020
06/05/20
​Dan Cunningham-Bryant, Ph.D.
​Ren Lab
Engineering Chromatin Loops to Interrogate Role
of Chromatin Structure in Oncogenesis
​05/01/20
​Dan Lorenz, Ph.D.
​Yeo Lab
Using direct RNA sequencing to uncover RNA
modifications in cancer
​04/03/20
​Victoria Wu, Predoc Trainee
​Gutkind Lab
​Targeting cancer-specific innate immunity with
Zika virus
02/07/20
​August Williams, Predoc Trainee
​Hangauer Lab
​Revealing the Origin of Acquired Drug Resistance
Mutations in Cancer
​01/10/20
​Meghana Pagadala,
Predoc Trainee
​Carter Lab
​Germline Variants That Modify Tumor-Immune
Interactions
​12/06/19
​Erica Silva, Predoc Trainee
​Ideker Lab
​A Dynamic Perspective of DNA Damage Response
​11/01/19
​Ludmil Alexandrov, Ph.D.
​Assistance Professor, Department of 
Cellular and Molecular Medicine
​The Repertoire of Mutational Signatures in Human
Cancer
​10/04/19
​Debashis Sahoo, Ph.D.
​Assistant Professor, Department of
Pediatrics
​Developing Computational Models of Biological
Systems Using Boolean Implication Network
​09/06/19
​Bing Ren, Ph.D.
​Professor, Department of Cellular and
Molecular Medicine
Single-Cell Analysis of Genome Regulation
 ​2018 / 2019
06/07/19​
​Dan Lorenz, Ph.D.
​Yeo Lab
Using direct RNA sequencing to uncover RNA
modifications in cancer
05/03/19
​Jason Ear, Ph.D.
​Ghosh Lab
Subcellular localization of Daple regulates distinct
function during CRC progression
04/05/19
​Soo Park, MD
​Bajar Lab
DNA methylation patterns in response to
hypomethylating agents in MDS
​03/01/19
​Ayush Kishore, Ph.D.
​Gutkind Lab
Targeting G protein-coupled receptors in
glioblastoma stem cells
​02/01/19
​Carlos Medina, Predoc Trainee
​Dowdy Lab
​Role of MLL-AF9 fusion oncogene in
establisment, maintenance, and recurrence of
Acute Myeloid 
Leukemia
​01/04/19
​Myan Do, Predoc Trainee
​Willert Lab
WNT/FZD7 signaling in stem cells and cancer
​12/07/18
​Erica Silva, Predoc Trainee
​Ideker Lab
A dynamic perspective of DNA damage response
11/02/18
​Elaine Guo, Predoc Trainee
​Kolodner Lab
​Effects of FEN1 loss on cancer cells with BRCA1 or
BRCA2 defects
10/05/18
​Gene Yeo, Ph.D.
​Professor of Cellular and Molecular
Medicine
​RNA binding proteins: Engineers of human health
09/07/18
​Chris Putnam, Ph.D.
​Assistance Professor of Medicine
​Strategies for understanding results from large
genetic screens
 2017 / 2018
06/01/18 Tariq Rana, Ph.D. ​Professor of Pediatrics TBD 
05/04/18 Olivier Harismendy, Ph.D.
Asst. Professor of MedicineEvolution and Characterization of Chemo-Resistance at Single-Cell Resolution
04/06/18 S. Park, MD ​Bejar Lab  Genomic Correlates of IL-2 Response in Advanced Melanoma and Renal Cell Carcinoma
03/02/18 Ayush Kishore, Ph.D. Gutkind Lab  GNAQ-FAK Signaling in Ocular Melanoma 
02/02/18 Nathan Jameson Furnari Lab  Epigenetic regulation of EGFR in Glioblastoma 
01/05/18 Peter Ly, Ph.D. NIH Pathway to Independence Awardee  Rebuilding After Catastrophe: How Cell Division Errors Shape the Cancer Genome 
12/01/17 Elaine Guo, BS Kolodner Lab  Synthetic Lethal Targeting of BRCA-Deficient Cancer 
11/03/17 Jason Ear, Ph.D. Ghosh Lab  Dissecting the Role of DAPLE in Colorectal Cancer 
10/06/17 Carlos Medina, BS Dowdy Lab  Genomics of Recurrent Acute Myeloid Leukemia 
09/01/17 
Myan Do, BA Willert Lab  Wnt Receptor FZD7 in Cancers and ES Cells 
 2016 / 2017
06/02/17Jill Mesirov, Ph.D.Medicine Computational Cancer Genomics
05/05/17Nathan Jameson, Predoc TraineeFurnari Lab Understanding EGFRVIII Genomic Breakpoints through CRISPR Modeling
04/07/17Wendy Huang, Ph.D.Cellular and Molecular Medicine RNA Helicases and Non-Coding RNA in Immune Regulation
03/03/17Mohit Jain, MD, Ph.D.Medicine and Pharmacology Cancer Metabolomics
02/03/17Sven Heinz, Ph.D.Cellular and Molecular Medicine Medical Epigenomics in Chronic Lymphocytic Leukemia
01/06/17Matteo D'Antonio, Ph.D.Frazer Lab Kataegis Expression Signature in Breast Cancer is Associated with Late Onset, Better Prognosis and Higher HER2 Levels
12/02/16Jin Zhang, Ph.D.Pharmacology Spatiotemporal Regulation of Signaling
11/04/16 Hannah Carter, Ph.D.Medicine and Bioengineering Network Perturbing Cancer Mutations  
10/07/16 Guowei Wu​Fu Lab SRPK1 Inhibition in Cancer Signaling 
09/09/16 Debashis Sahoo, Ph.D. ​Pediatrics and Computer Science A New Framework to Understand Cancer Cells 
 2015 / 2016
05/06/16 Christie Eissler, Ph.D. ​Zhou Lab The Role of Sumoylation in Chromosome Translocation 
04/01/16 Guowei WuFu Lab  SRPK1: A Tumor Suppressor, Oncogene or Both? 
03/04/16 Elaine Guo ​Kolodner Lab  Synthetic Lethality Relationships Involving Genome Instability 
02/05/16 Nicholas Kalogriopoulos Ghosh Lab  Cross-Talk Between RTKs and Trimeric G Proteins 
01/08/16 Nathan Jameson Furnari Lab  Chromatin Dynamics and Dysregulation Caused by EGFRvIII Deletion in Glioblastoma 
12/04/15 Xiang-Dong Fu, Ph.D. Fu Lab  SRPK1: A Potential Key Cancer Target 
11/06/15 Peter Ly, Ph.D. Cleveland Lab  Fragmentation and Reassembly of a Specific Human Chromosome in Micronuclei 
10/02/15 Kelly Frazer, Ph.D. Pediatrics   Identification of Driver Mutations in Distal Regulatory Elements in Breast Cancer 
09/04/15 Clark Chen, MD/Ph.D.  Neurosurgery  Epigenetic Regulation of Glioblastoma Tumor Initiation 
2014 / 2015 
07/10/15 Jun Bao Fan, Ph.D. Zhang Lab  ISG15/Protein in Cancer Development: Friend or Foe? 
06/05/15 Sebastian Gomez-Cavazos, Ph.D. Oegema Lab  Exploring the roles of Plk1 and the Chromosome Passenger Complex during Cytokinesis 
05/01/15 Aaron Springer Dowdy Lab  Treating Cancer with BioReversible Prodrug RNAi Therapeutics 
04/03/15 Cara Bickers Traver Lab  Lineage Tracing of Hematopoietic Stem and Progenitors in Zebrafish 
03/06/15 Nicholas Kalogriopoulos Ghosh Lab  Role of G Proteins in Tumor Glucophagy: Lessons Learned From Diabetes 
02/13/15 Christie Eissler, Ph.D. Zhou Lab  Investigating the Role of Protein SUMOylation in Cell Cycle Dynamics and Genome Stability 
01/09/15 Gen-Sheng Feng, Ph.D. Feng Lab  Dissecting the Contradictory Roles of Signaling Molecules in Liver Cancer 
12/05/14 Maricel Gozo, Ph.D. Cheresh Lab  Stress-Induced Reprogramming of Epithelial Cancers 
11/07/14 Pradipta Ghosh, MD/Ph.D. Ghosh Lab 

Molecular Engineering to Explore, Access, and Modulate a Cancer Cell's Signaling Code

10/03/14 Paul Mischel, Ph.D. Mischel Lab  Targeting EGFR-P13-mTOR Signaling: A Central Role of mTORC2 in Cancer Metabolic Reprogramming 
09/05/14 Karen Oegema, Ph.D. Oegema Lab  Dynamic Cytoskeletal Rearrangement Underlying Cell Division in Cancer 
2013 / 2014
07/11/14 Steve Dowdy, Ph.D. Dowdy Lab  Death of a Dogma, Cyclin D Activates Rb by Mono-Phosphorylation 
06/06/14 Aaron Springer Dowdy Lab  Treating Cancer with BioReversible siRNN Produg RNAi Therapeutics 
05/02/14 Julia Nussbacher Yeo Lab  Roles of RNA Binding Proteins in RNA Metabolism and Protein Translation 
04/04/14 Amelia Richardson Desai Lab  Functional Analysis of Cohesin Mutants in Human Cancer 
03/07/14 Trey Ideker, Ph.D. Ideker Lab  Mapping the Genetic Networks of Cancer 
02/07/14 Kun-Liang Guan, Ph.D. Guan Lab  The Hippo-YAP Pathway in Organ Size Control and Tumorigenesis 
01/10/13 Cara Bickers Traver Lab  Building Tools for a Zebrafish Leukemia Model
12/06/13 Frank Furnani, Ph.D. Furnani Lab  EGF Receptor in Glioma Biology: Therapeutic Target and a Multifaceted Driver of Pathogenicity
11/01/13 Peter Ly, Ph.D. Cleveland Lab  Chromosomal Fragmentation Chromothripsis in Cancer
10/04/13 Maricel Gozo, Ph.D. Cheresh Lab  Determining Novel Strategies to Overcome EGFR Resistance 
09/06/13 David Traver, Ph.D. Traver Lab  Normal and Neoplastic Hematopoiesis 
2013 / 2012
07/05/13 Richard Kolodner, Ph.D. Kolodner Lab  DNA Damage Repair Mechanisms Drive Cancer 
06/07/13 Stephanie Weng Zhang Lab  Exploring Mechanisms to Reduce Leukemogenic Potential of AML-1-ETO 
05/03/13 Alex Hamil Dowdy Lab  siRNN Induced RNAi Responses to Treat Cancer 
04/05/13 Gene Yeo, Ph.D. Yeo Lab  Studies of RNA Binding Proteins Associated with Neurological Disease 
02/01/13 Brian Thacker 
Esko Lab  The Role of Heparan Sulfate 3-O Sulfation in Tumor Angiogenesis
01/04/13 Nicholas Vinckier Sander Lab  The Roles of SOX9, HES1, and NGN3 in Progression of Pancreatic Ductal Adnocarcinoma (PDAC)  
12/07/12 Julia Nussbacher Yeo Lab  RNA Binding Protein Regulation of RNA Metabolism 
11/02/12 Pradipta Ghosh, MD/Ph.D. Ghosh Lab  Transactivation of G-Protein by Tyrosine Kinases 
10/05/12 Kirsten Ludwig, Ph.D. Wang Lab  Stem Cell Growth Factor Control of Colon Cancer Invasiveness 
09/07/12 Amelia Richardson Desai Lab  Cohesin Complexes Mutations in Cancer 
2011 / 2012
06/01/12 Nicholas Vinckier Sander Lab  Notch Signaling in Progression of Pancreatic Ductal Adenocarcinoma (PDAC) 
05/04/12 Alex Hamil Dowdy Lab  Induction of Synthetic Lethal RNAi Response to Treat Cancer 
04/06/12 Anthony Beas Farquhar Lab  Gas Regulation of EEA1 Shuts Down Proliferation Signaling Through GIV (Girdin) 
03/02/12 Stephanie Weng Zhang Lab  Haploinsufficiency in t(8;21) AML Patients 
02/03/12 Brian Thacker Esko Lab  Heparan Sulfate 3-O Sulfotransferases in Cancer 
01/06/12 Jean Wang, Ph.D. Wang Lab  Resistance of Leukemic Stem Cells to Oncogene Targeted Therapies 
12/02/11 Spencer Wei Yang Lab  Epithelial-Mesenchymal Transition (EMT) Programming During Breast Cancer Metastasis 
11/01/11 Brian Meade Dowdy Lab  Development of Novel RNAi Therapeutics with New Synthetic Chemistr
10/07/11 Kirsten Ludwig, Ph.D. Wang Lab  p190RhoGap and Anillin Modulation of Rho-GTP During Cleavage Furrow Formation 
09/09/11 Steve Dowdy, Ph.D. Dowdy Lab  Regulation of G1 Cell Cycle Progression in Cancer