Cardiovascular Physiology Research Laboratory

The cardiovascular physiology research laboratory at UCSD/VA San Diego Medical Center focuses on:

  •  Novel basic science inquiry into mechanisms of myocardial ischemia-reperfusion injury, cardiac remodeling and heart failure
  • The study of volatile and opioid anesthetics as they relate to ischemia-reperfusion injury
  • Lab uses state-of-the-art physiological monitoring, molecular biology, primary cell culture, transgenic animals, gene therapy, immunohistochemistry and electron microscopy to address novel mechanisms for
    cardiac injury and remodeling
  • Teams has several collaborations with other clinical and research departments at UCSD
    including the Division of Cardiology, the Department of Pharmacology, and Department of Cellular and Molecular
    Medicine and the UCSD Cancer Center
  • Principal investigator David M. Roth, Ph.D., M.D., and  co-investigators, Piyush M. Patel, M.D., Hemal H. Patel, Ph.D. and Yasuo Tsutsumi, M.D., Ph.D.
  • Lab and its investigators are funded by the National Institutes of Health, The Veterans Administration and the American Heart Association
  • Lab is productive and has published 18 manuscripts in the years 2006-2007 and has made presentations at the American Society of  Anesthesiologists annual meeting 2006, the American Heart Association annual meeting 2006 and at the Experimental Biology meeting 2007