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Transgenic Mouse: Getting Started

Where do I start?

So you want to make a transgenic or knockout line? Here's what you'll need to have before we can begin work on your project:

  • Approved animal protocol in place
  • DNA or RNA prepared using protocols provided by Core
  • Plan in place for screening ES cells (for KO)
  • Assigned animal space as destination for mice
  • Plan in place for screening pups
  • Trained personnel to breed mice, cut tails, and screen DNA
  • UC San Diego index number or an off-campus purchase order
  • UC San Diego Transgenic Core Request For Services

If you require a support letter from the Transgenic Core for your grant submissions, please contact