Transgenic Mouse


Pamela Mellon, PhD
Professor of Reproductive Medicine and Neuroscience
Phone: 858-534-1140


For CRISPR Microinjection inquiries, email Jun Zhao, or Ella Kothari,

For Pronuclear Microinjection inquiries, email Jun Zhao,

For Embryo Rederivation, Embryo Cryopreservation, In-Vitro Fertilization inquiries, email Jun Zhao,

For Sperm Cryopreservation inquiries, email Jun Zhao,

For Embryonic Stem Cell inquiries, email Ella Kothari,

For Blastocyst Injection inquiries, email Ella Kothari,

Service profile


The Transgenic Mouse shared resource is a state-of-the-art facility that has an outstanding track record in the production of genetically altered mice. Transgenic mice carrying new or novel genes are created by microinjection of DNA into the pronuclei of fertilized eggs. Knock-out mice lacking specific genes of interest are created by homologous recombination in embryonic stem cells followed by injection into blastocysts to create chimeric mice. Highly experienced personnel produce transgenic and knock-out mice for UC San Diego investigators at very reasonable cost and with very short lead times.

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