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Photoacoustic Imaging/Ultrasound Imaging

  • ​VevoLAZR (Fujifilm/VisualSonics)

The VevoLAZR is an in vivo preclinical photoacoustic imager developed by VisualSoncics/Fujifilm. It is based on the photoacoustic effect where short pulses of light are optically absorbed inducing an ultrasound signal. Hence, photoacoustic images are ultrasound images of optical absorption with the advantage of superior ultrasound depth penetration and spatial resolution over solely optical absorption imaging. Furthermore, the VevoLAZR employs a tunable laser enabling photoacoustic imaging spectroscopy. Intrinsic optical absorbers in tissue, namely oxy- and deoxy-hemoglobin, can provide images of total hemoglobin concentration and hypoxia. Optically-absorbing contrast agents are used for photoacoustic molecular imaging. The VevoLAZR is seamlessly integrated with a Vevo2100 high-frequency, in vivo preclinical ultrasound imager allowing real-time co-registered photoacoustic and ultrasound images.

  • Vevo2100 (Fujifilm/VisualSonics)

The Vevo2100 is an in vivo preclinical ultrasound imager developed by VisualSoncics/Fujifilm. It employs high frequency ultrasound for high-resolution, real-time ultrasound imaging. Standard ultrasound imaging (B-mode, M-mode, PW, Color Doppler, Power Doppler, Non-linear contrast agent imaging, 3D mode) is available. An advanced physiological monitoring unit tracks temperature, ECG, heart rate, blood pressure and the comprehensive software analysis tools include VevoStrain (myocardial), VevoCQ (perfusion, contrast), and VevoVasc (cardiovascular function) plus several others.

The VevoLAZR/Vevo2100 system was funded by a NIH S10 grant, PI Dr. Hall. Dr. Hall is available for consulting as needed