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Scholar Publications


Phillip Bartels, PhD

Clausen, T. M., Sandoval, D. R., Spliid, C. B., Pihl, J., Perrett, H. R., Painter, C. D., Narayanan, A., Majowicz, S. A., Kwong, E. M., McVicar, R. N., Thacker, B. E., Glass, C. A., Yang, Z., Torres, J. L., Golden, G. J., Bartels, P. L., Porell, R. N., Garretson, A. F., Laubach, L., Feldman, J., … Esko, J. D. (2020). SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. Cell, 183(4), 1043–1057.e15. https://doi.org/10.1016/j.cell.2020.09.033. PMCID: PMC7489987.


Julia Callender, PhD

Aguilar-Calvo P, Callender JA, and Sigurdson CJ. Short and sweet: How glycans impact prion conversion, cofactor interactions, and cross-species transmission. PLoS Pathogens 2021 Jan; 17(1): e1009123. PMCID: PMC7808606

Callender JA, Sevillano AM, Soldau K, et al. Prion protein post-translational modifications modulate heparan sulfate binding and limit aggregate size in prion disease. Neurobiol Dis. 2020;142:104955. doi:10.1016/j.nbd.2020.104955. Epub 2020 May 24. PubMed PMID: 32454127.

Dillon Chen, MD, PhD

Hane M, Chen DY, Varki A. Human-specific Microglial Siglec-11 Transcript Variant has the Potential to affect Polysialic Acid-Mediated Brain Functions at a Distance. Glycobiology. 2020 Aug 26:cwaa082. doi: 10.1093/glycob/cwaa082. Online ahead of print. PMID: 32845322


Sun-Mi Choi, MD, PhD

Choi, Christiansen, DeConde, Doherty, Nizet;Choi, Christiansen, DeConde, Doherty, Nizet; Dysfunctional mucosal immune defense in CRS increase susceptibility to Staphylococcus Aureus. JACI Vol 147 Number 2 AB155. Feb 2021. Abstract 495

Choi SM, DeConde A, Christiansen SC, Nizet V. Staphylococcus Aureus Induces IL-33, TSLP, and Muc5AC production by AERD Nasal Epithelium [Abstract for AAAAI Annual Meeting]. J Allergy Clin Immunol. 2019 Feb;143(2), Supplement Page AB230. doi: 10.1016/j.jaci2018.12.701.

Michelle Ducasa, PhD

Pessentheiner AR, Ducasa GM, Gordts PLSM. Proteoglycans in Obesity-Associated Metabolic Dysfunction and Meta-Inflammation. 2020 May 19;11:769. doi: 10.3389/fimmu.2020.00769. eCollection 2020. PubMed PMID: 32508807; PubMed Central PMCID: PMC7248225.

So-Young Kim, PhD

Kim, SY, Gupta, P, Johns, S, Zuniga, E, Fuster, MM. Genetic alteration of heparan sulfate in dendritic cells inhibits inflammation and facilitates pathogen clearance during PR8 influenza A virus infection. Scientific Reports. 2021. 
In revision.

Kim, SY, Jin, W, Sood, A, Montgomery, DW, Grant, OC, Fuster, MM, Fu, L, Dordick, JS, Woods, RJ, Zhang, F, and Linhardt, RJ. Characterization of heparin and severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike glycoprotein binding interactions. Antiviral Research. 2020 Sept;181:104873. doi: 10.1016/j.antiviral.2020.104873. Epub 2020 July 10. PubMed PMID: 32653452; PubMed Central PMCID: PMC7347485.

Kim, S.Y., Jin, W., Sood, A., Montgomery, D.W., Grant, O.C., Fuster, M.M., Fu, L., Dordick, J.S., Woods, R.J., Zhang, F. and Linhardt, R.J., April 2020. Glycosaminoglycan binding motif at S1/S2 proteolytic cleavage site on spike glycoprotein may facilitate novel coronavirus (SARSCoV-2) host cell entry. bioRxiv 2020.04.14.041459; doi: https://doi.org/10.1101/2020.04.14.041459

Gupta P, Johns SC, Kim SY, El Ghazal R, Zuniga EI, Fuster MM. Functional Cellular Anti-Tumor Mechanisms are Augmented by Genetic Proteoglycan Targeting. Neoplasia. 2020 Feb;22(2):86-97. doi: 10.1016/j.neo.2019.11.003. Epub 2019 Dec 30. PubMed PMID: 31896526; PubMed Central PMCID: PMC6940629.

Ryan Porell, PhD

Clausen, T. M., Sandoval, D. R., Spliid, C. B., Pihl, J., Perrett, H. R., Painter, C. D., Narayanan, A., Majowicz, S. A., Kwong, E. M., McVicar, R. N., Thacker, B. E., Glass, C. A., Yang, Z., Torres, J. L., Golden, G. J., Bartels, P. L., Porell, R. N., Garretson, A. F., Laubach, L., Feldman, J., … Esko, J. D. (2020). SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. Cell, 183(4), 1043–1057.e15. https://doi.org/10.1016/j.cell.2020.09.033. PMCID: PMC7489987.

Gonzalez-Gil A, Li TA, Porell RN, Fernandes SM, Tarbox HE, Lee HS, Aoki K, Tiemeyer M, Kim J, Schnaar RL. Isolation, identification, and characterization of the human airway ligand for the eosinophil and mast cell immunoinhibitory receptor Siglec-8. J. Allergy Clin Immunol. 2020 Aug 11:S0091-6749(20)31107-6. doi: 10.1016/j.jaci.2020.08.001. Epub ahead of print. PMID: 32791164.

Porell RN, Honigfort D, Godula, K. Reprogramming the tumor microenvironment with macrophage-targeted glycopolymers [Abstract for SFG 2019 Meeting]. Glycobiology. 2019 Dec;29(12):934, Abstract 66. doi: 10.1093/glycob/cwz083.

Ryan Weiss, PhD

Weiss, R.J.*; Spahn P.N.*; Chiang A.W.T.; Liu Q.; Li J.; Hamill K.M.; Rother S.; Clausen T.M.; Hoeksema, M.A.; Timm, B.M.; Godula, K.; Glass, C.K.; Tor, Y.; Gordts P.L.S.M.; Lewis N.E.; Esko J.D. Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate. Nature Chemical Biology (Feb 2021) Accepted

Weiss RJ, Spahn PN, Toledo AG, Chiang AWT, Kellman BP, Li J, Benner C, Glass CK, Gordts PLSM, Lewis NE, Esko JD. ZNF263 is a transcriptional regulator of heparin and heparan sulfate biosynthesis. Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9311-9317. doi: 10.1073/pnas.1920880117. Epub 2020 Apr 10. PubMed PMID: 32277030; PubMed Central PMCID: PMC7196839.

Weiss, R.J.; Rother, S.; Gregio, A.; Oukoloff, K.; Heynen-Genel, S.; Ballatore, C.; Esko, J.D. Drug Discovery for Multiple Hereditary Exostoses. FASEB J. April 2020. (Conference Abstract)