The Clinical and Translational Research Institute (CTRI) is part of a national
Clinical and Translational Science Award (CTSA) consortium, led by the
National Institutes of HealthNational Center for Advancing Translational Sciences (NCATS). Established in 2010, CTRI provides infrastructure and support for basic, translational and clinical research throughout the San Diego region to bring discoveries from the laboratory to the bedside, and facilitates training and education of the next generation of researchers. CTRI carries out its activities in collaboration with institutional and corporate partners and currently has more than 1,300 members. The
CTRI News and Funding Opportunities is a monthly newsletter.
CTRI Special Announcements
CTRI Announces New Category of Vouchers for CCBB Services
UC San Diego Altman Clinical and Translational Research Institute (ACTRI) is pleased to announce the addition of a new Vouchers category to support Center for Computational Biology and Bioinformatics (CCBB) services. This new level of support for CCBB includes three funding tiers: $500 for pre-award planning and consultation; $5,000 for an early stage unfunded project; and $25,000 for expanding an existing project that is already federally funded. The new CCBB category is for data analysis only. Vouchers are not cash awards and can only be used for in-kind services. Services are contingent upon resource availability. More information and eligibility requirements are
CTRI and IEM Invite Applications for 2017 Galvanizing Engineering in Medicine (GEM) Awards, Phase I
Deadline December 16, 2016
CTRI Invites Applications for 2017 Dissemination and Implementation Research Pilot Grants
Deadline November 7, 2016
CTRI Invites Applications for 2017 Academic-Community Partnership Pilot Project Grants
Deadline November 7, 2016
UC CAI Invites Applications for NHLBI Tech Grants
Letters of Intent Due November 18, 2016
UC CAI Offers NHLBI Stimulus Grants
Submissions Due November 14-23, 2016
CTRI Vouchers for CTRI Research Services (In-kind)
Vouchers for the Center for Computational Biology and Bioinformatics services are now available. Eligible: Unfunded Projects Designed to Gather Preliminary Data for Grant Submissions or CTRI Pilot Projects Career Development Awards (K-series only; UC San Diego only) and CTRI KL2 Awardees
CTRI Seeks Applications for KL2 Training Support for Junior Faculty
Deadline November 29, 2016
NCATS Open Funding Opportunities
CTRI News and Features
1st row: Bhaskar Rao, PhD; Sebastian Obrzut, MD; Bongyong Song, PhD. 2nd row: Frank Talke, PhD; Thomas Savides, MD. 3rd row: Karen Christman, PhD; Marianna Alperin, MD, MAS; Sheng Xu, PhD; Robert Owens, MD
UC San Diego ACTRI and IEM Announce 2016 Galvanizing Engineering in Medicine Awardees
Four physician-engineer teams from UC San Diego have been selected to receive the 2016 Galvanizing Engineering in Medicine (GEM) awards, which were created to bring engineers and clinicians together to develop innovative technology solutions to challenging problems in medical care. GEM is a program of UC San Diego Altman Clinical and Translational Research Institute (ACTRI) and UC San Diego Institute of Engineering in Medicine (IEM). “We are excited to support these impressive projects, which exemplify disruptive innovations to make a difference in the lives of our patients,” said Gary S. Firestein, MD, director of the ACTRI and dean and associate vice chancellor of translational medicine at UC San Diego. This year’s projects center on developing better ways to monitor patient sleep during recovery, improved treatments for pelvic floor disorders, safer and less expensive instrumentation for internally viewing organs, and methods for obtaining clinical images more quickly.
CTRI Pilot Project Paves Way to US Patent for UC San Diego Researcher Franco
In 2010, Alessandra Franco, MD, PhD, received a small pilot project grant from the newly established Clinical and Translational Research Institute (CTRI) to study how natural regulatory T cells (nTregs) respond following standard treatment in Kawasaki disease (KD). Her project focused on characterizing T cell lineages in KD, which causes acute inflammation of the coronary arteries in young children, and is generally treated with intravenous immunoglobulin (IVIG). Natural regulatory T cells modulate immunity and regulate inflammatory conditions. Results generated from her study led to a U.S. patent award in 2015 for the discovery of peptide compositions to expand nTregs that recognize a specific region of immunoglobulins. This is a novel process for IVIG function and appears to be critical to resolve KD. Franco’s discovery centers on identifying certain peptides to expand nTregs with implication for a wide range of vascular inflammatory conditions and autoimmune diseases. Peptides are small sequences of proteins; Franco discovered the immunodominant peptides derived from the Fc of immunoglobulin.
Stay tuned for a feature about CTRI pilot project awardee Adriana Tremoulet, MD, associate director of the Kawasaki Disease Research Center at UC San Diego, who collaborates with Dr. Franco on Kawasaki disease.
In This Issue
CTRI Hosts Communications Seminar for Early Career “K” Awardees
The Clinical and Translational Research Institute (CTRI) is hosting a year-long career development seminar series, “Communicating: Your Academic Life Depends on It,” for early career “K” awardees from UC San Diego, San Diego State University, and CTRI partner institutions. The fifth session in the series is scheduled for Tuesday, November 1. Michael Ziegler, MD, will present “Responding to Reviewer’s Criticisms.” The session will take place at the Altman CTRI building, specific room TBD. RSVP is required to
CTRI Seminar Series
“Imaging the Dynamic Restless Brain” will be presented by Thomas Liu, PhD, director of the Center for Functional MRI, UC San Diego, on Tuesday, November 15, at 3 p.m. at the School of Medicine Campus.
Cite the Grant
Don’t forget to cite the grant!
To help ensure resources are available for future research,
please cite the UCSD CTRI CTSA grant.
Projects and Publications using UCSD CTRI resources must cite the UCSD CTRI grant and follow the NIH Public Access Policy.
CTRI News and Funding Opportunities
Gary S. Firestein, MD
Director of CTRI
Chief Administrative Officer