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ACTRI News and Funding Opportunities-July 2017

UC San Diego Altman Clinical and Translational Research Institute Newsletter:
August 2017, Vol. 2, Issue 8

UC San Diego Altman Clinical and Translational Research Institute (ACTRI) is part of a national Clinical and Translational Science Awards (CTSA) consortium, led by the National Institutes of HealthNational Center for Advancing Translational Sciences (NCATS). Established in 2010, ACTRI provides infrastructure and support for basic, translational and clinical research throughout the San Diego region to bring discoveries from the laboratory to the bedside, and facilitates training and education of the next generation of researchers. ACTRI carries out its activities in collaboration with institutional and corporate partners and currently has more than 1,400 members. The ACTRI News and Funding Opportunities is a monthly newsletter.

ACTRI Special Announcements

2017 Galvanizing Engineering in Medicine Awardees

2017 GEM awardees from left: (top row) James Friend, PhD; Drew Hall, PhD; Louise Laurent, MD, PhD; Yu-Hwa Lo, PhD; and Elliott R. McVeigh, PhD; (bottom row) Anna Narezkina, MD; Alexander Norbash, MD; Frank Talke, PhD; and Robert Weinreb, MD.

ACTRI and IEM Announce 2017 Galvanizing Engineering in Medicine Awardees

Four physician-engineer teams from UC San Diego have been selected to receive the 2017 Galvanizing Engineering in Medicine (GEM) awards. GEM, an initiative of UC San Diego Altman Clinical and Translational Research Institute (ACTRI) and UC San Diego Institute of Engineering in Medicine (IEM), brings engineers and clinicians together to develop innovative technologies that can be applied to solving challenging problems in medical care. This year’s projects address challenges in the areas of cardiology, ophthalmology, radiology, and reproductive medicine. “GEM truly bridges medicine and engineering to find unique solutions to pressing medical concerns,” said Deborah Spector, PhD, chair of the GEM Committee and director of the ACTRI Translational Research Alliance. “We are excited about this year’s outstanding projects, selected for their creativity and potential to improve health.” Read more

View the 2017 GEM Project Abstracts

Funding Opportunities

ACTRI and Pfizer Offer Pre-Proposal Meetings for Upcoming Drug Discovery Collaboration Opportunity

ACTRI Vouchers for ACTRI Research Services (In-kind)

  • Allowance for Vouchers to Supplement Two Types of NIH-Funded Studies for ACTRI Clinical Services Only
  • Recent Addition of CCBB Vouchers

Eligible: Unfunded Projects Designed to Gather Preliminary Data for Grant Submissions or ACTRI Pilot Projects, Career Development Awards (K-series only; UC San Diego only) and ACTRI KL2 Awardees. In addition, Vouchers can potentially be used to supplement two types of NIH-funded studies for ACTRI clinical services only.

NCATS Open Funding Opportunities

Courtesy Postings

NEW** UC San Diego Seeks Proposals for Pilot Studies on the Use of Technology to Preserve Independence in Older Adults

NEW** UC San Diego Seeks Proposals for Research and Education Support Related to the Use of Technology to Preserve Independence in Older Adults

ACTRI News and Features

Anjan Debnath, PhDACTRI KL2 Awardee Debnath Publishes Findings about Compounds in Desert Bush to Treat Parasitic Infections

ACTRI KL2 awardee Anjan Debnath, PhD, co-led a research team studying the effects of compounds produced by the desert creosote bush on treating deadly parasitic infections. The findings are published in the Public Library of Science (PLOS) Journal and featured in a UC San Diego Health story, “Compounds in Desert Creosote Bush Could Treat Giardia and ‘Brain-eating’ Amoeba Infections.” Debnath, an assistant adjunct professor at Skaggs School of Pharmacy and Pharmaceutical Sciences at UC San Diego, is the co-principal investigator of the study. In 2016, he received an ACTRI KL2 grant, which supports him, in part, on this study. The KL2 is an award for junior faculty that offers training and mentored research experience for up to three years. Debnath’s KL2 project focuses on a novel approach to inhibiting a critical enzyme in brain eating amoeba. “Support from the KL2 program was incredibly valuable in expanding the antiparasitic activity study of compounds isolated from the creosote bush to identifying a target in Naegleria fowleri,” said Dr. Debnath. Read more

Read the UC San Diego Health story

Read the abstract of the newly published PLOS paper. The article, Larrea tridentata: A novel source for anti-parasitic agents active against Entamoeba histolytica, Giardia lamblia and Naegleria fowleri, is available online in the August 9 issue of PLOS Neglected Tropical Diseases.

Trial Innovation Network Announces Two New Opportunities in Efficacy to Effectiveness Trial Design

The Trial Innovation Network (TIN) is now offering researchers two new opportunities in Efficacy to Effectiveness (E2E) trial design. Through the E2E approach, an effectiveness trial would commence seamlessly upon completion of the efficacy trial. E2E trials are prospectively designed to address the effectiveness and safety gaps that often occur in standard randomized controlled trials, and offer an opportunity for improved understanding of how a treatment will work in more usual real-world clinical settings. New E2E opportunities to help improve your research are the E2E Design Lab in March 2018 and the E2E Consultations. The registration deadline for the E2E Design Lab is Sept. 15, 2017. Read more

More information about the TIN initiative and the TIN Hub Liaison Team at UC San Diego

ACTRI Building

Photo by Paul Turang©

ACTRI Building Garners 2017 Design Award

The Altman Clinical and Translational Research Institute (ACTRI) building was named Best Project, Southern California in the Higher Education/Research category of the 2017 Engineering News-Record (ENR) California awards. ZGF Architects designed the building, which opened in 2016. View the list of winners

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In This Issue

Upcoming Seminars

ACTRI Seminar Series

Cardiac Rehabilitation: Current and Future Directions

Tuesday, September 12, 2017
Lunch and Lecture

Pam R Taub, MDSeminar presented by Pam R. Taub, MD, FACC, director of Step Family Foundation Cardiovascular Rehabilitation and Wellness Center, and Associate Professor of Medicine, University of California San Diego, at the Altman Clinical and Translational Research Institute Building.

The seminar is free, but registration is required for the lunch. Read more about the series and register.

ACTRI Communications Seminar for Early Career “K” and Equivalent Awardees

UC San Diego Altman Clinical and Translational Research Institute (ACTRI) is hosting a year-long career development seminar series, “Communicating: Your Academic Life Depends on It,” for early career “K” and equivalent Career Development awardees from UC San Diego, San Diego State University, and ACTRI partner institutions. The first session in the series is scheduled for Tuesday, September 5. The talk, “Publishing from the Editor’s Perspective,” will follow a general orientation. The session will take place at the ACTRI building. RSVP is required to Read more

ACTRI Services

Clinical Coordinator

ACTRI Clinical Coordinator Services

ACTRI clinical coordinators have the expertise to guide researchers on resources available for any stage of clinical research. They can assist in screening study participants, ensuring continuity in data collection, maintaining data, or in carrying out other tasks such as conducting study visits and obtaining and shipping specimens. From left are ACTRI clinical coordinators Donna Brusch, David Ashley, Len Lazaro and Baharin Abdullah. Find out how the ACTRI clinical coordination service can help you or contact Clinical Research Program Manager David Rodriguez

Cite the Grant

citegrantdocDon’t forget to cite the grant!

To help ensure resources are available for future research, please cite the UCSD ACTRI CTSA grant.

Projects and Publications using UCSD ACTRI resources must cite the UCSD ACTRI grant and follow the NIH Public Access Policy.

NIH National Center for Advancing Translational Sciences (NCATS)


ACTRI News and Funding Opportunities

Gary S. Firestein, MD
Director of ACTRI

Eric Mah
Chief Administrative Officer

Patricia Wieser
Communications Director

Tracy Dezenzo
Graphic Designer


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