CTRI News and Funding Opportunities - February 2016

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UC San Diego Clinical and Translational Research Institute Newsletter:
February 2016, Vol. 1, Issue 2

The CTRI is part of a national Clinical and Translational Science Award (CTSA) consortium, led by the National Institutes of Health National Center for Advancing Translational Sciences (NCATS). Established in 2010, CTRI provides infrastructure and support for basic, translational and clinical research throughout the San Diego region to bring discoveries from the laboratory to the bedside, and facilitates training and education of the next generation of researchers. CTRI carries out its activities in collaboration with institutional and corporate partners and currently has more than 1,000 members.

CTRI Special Announcements

The CTRI Announces New Vouchers Program

In-kind Services Related to Clinic, Bioinformatics, Biostatistics, and Labs Available

The CTRI is pleased to introduce the availability of vouchers for CTRI research services. These vouchers are designed to support early-stage projects that need preliminary data for subsequent applications for federal or foundation grants. They are not cash awards and can only be used for in-kind services, including those related to the clinic, biostatistics, bioinformatics, coordinator, and labs. Services are contingent upon resource availability. Vouchers are for services up to $5,000 and replace the catalyst grant program. To apply for a voucher, please fill out a CTRI Service Request Form.

Only unfunded projects that are designed to gather preliminary data for a grant submission are eligible. Exceptions for funded projects include CTRI Pilot Project awardees, CTRI KL2 awardees and CTRI TL1 awardees. For any project requiring IRB or IACUC approval, the voucher application should be submitted in conjunction with the IRB/IACUC submission. Voucher applications can be submitted at any time. Awarding the CTRI voucher is contingent upon the availability of the services requested. Read more

Funding Opportunities

GEM

CTRI and IEM Seek Engineering Applicants for Phase II of the Galvanizing Engineering in Medicine Awards
Deadline for Phase II Proposals: April 29, 2016

California National Primate Research Center 2016 Call for Pilot Project Letters of Intent
Deadline for Letters of Intent: February 15, 2016

Reminder: Applications Invited for UC Cures for Alzheimer’s Disease Initiative
Deadline for Concept Proposals: March 14, 2016

Reminder: CTRI and Pfizer’s Centers for Therapeutic Innovation (CTI) Announce the Call for Proposals: Biotherapeutic and Small-Molecule Targets
Deadline for Pre-proposals: February 26, 2016

CTRI News and Features

The CTRI Welcomes New Biostatistician Wells

Alan Wells, M.S.Alan Wells, M.S., has joined the CTRI Biostatistics Group as a biostatistician. Wells has extensive experience implementing statistical methods to execute a wide range of analyses. Prior to coming to UC San Diego, he was a statistical data analyst at Washington University School of Medicine in St. Louis, where his work had a special emphasis on statistical genomics. Wells received a bachelor’s degree in biomedical engineering from George Washington University in Washington, D.C., in 2012 and a master’s of science degree in biostatistics from Washington University in 2013.

“We are delighted to have Alan Wells join the CTRI Biostatistics team. His background in statistical data analysis and experience supporting genomics studies uniquely qualify him for this position,” said Ronghui (Lily) Xu, Director of CTRI Biostatistics.

At the CTRI, he provides biostatistics consultation for study design and data analysis. He is located at the CTRI East Campus Office Building, as well as onsite part of the week at Rady Children’s Hospital, working with CTRI senior biostatistician James Proudfoot on data analysis. Wells also helps with CTRI’s free walk-in biostatistics consultation on Wednesday afternoons.

“I always liked applying numbers to biology,” Wells said. “Statistics interests me because I like the challenges of figuring out biology, as well as figuring out how to help people – and improving human health is our true goal.”

For more information about how Wells or other members of the CTRI Biostatistics team can help you with your research project, please visit CTRI Biostatistics.

2015 GEM Physician-Engineer Teams Collaborate on Ophthalmology and Cardiovascular Projects

GEM recipiants

During the fall, four physician-engineer teams from UC San Diego were selected as the 2015 recipients of the Galvanizing Engineering in Medicine (GEM) awards. GEM, an initiative of the CTRI and the UC San Diego Institute of Engineering in Medicine (IEM), supports projects that identify clinical challenges for which engineering solutions can be developed and implemented to improve health care. The 2015 GEM teams, each of which include one physician and at least one engineer, are collaborating on projects that range from retinal prostheses to left-ventricular blood stasis and from ventricular fibrillation to intraocular pressure.

The four teams and their projects include:

Gert Cauwenberghs, PhD
Gabriel Silva, PhD
William Freeman, MD
Micropower Integrated Nano-engineered Retinal Interface

Juan Carlos del Alamo, PhD
Andrew Kahn, MD, PhD
Solution: Development of Patient-specific Indices of Left-ventricular Blood Stasis by Echocardiographic Imaging and Analyses of Intraventricular Flow

Andrew D. McCulloch, PhD
David Krummen, MD
Development of a Non-Invasive Quantitative Tool to Detect and Localize Human Ventricular Fibrillation Mechanisms

Donald J. Sirbuly, PhD
Robert Weinreb, MD
Continuous and Direct Intraocular Pressure Monitoring via Fluid-sensitive 3D Photonic Crystal Implants

“We were delighted to announce last year’s GEM teams. Their projects demonstrate great potential for developing innovative answers to ophthalmology and heart-related questions,” said Deborah Spector, PhD, Chair of the GEM Committee and Director of CTRI Translational Research Alliance. “As the 2015 GEM awardees progress on their collaborations, we are in the midst of the 2016-17 GEM solicitation and are seeking proposals to the Phase I clinician proposals.”

Read more about the 2015 GEM awardees

Read more about the request for GEM Phase II engineering proposals

Editorial/Grant Writing Services Added to CTRI Repertoire

Angela Felker, PhDThe CTRI recently added the services of an Editorial Coordinator to assist with large-scale interdisciplinary projects, such as P30s, P50s, T32s (aside from tables) and U awards. Investigators are welcome to contact Angela Felker, PhD, for assistance with writing and technical editing, organizing and managing timelines to meet submission deadlines, engaging key faculty and staff on collaborative projects, and ensuring all grant proposal documents are in place. Dr. Felker has experience preparing and applying for grant proposals, creating seamless documents from multiple author contributions, and the ability to communicate complex concepts to a variety of audiences.

Investigators may contact Angela Felker, PhD, at afelker@ucsd.edu for further information.

The CTRI Expands Ultrasound Services

Minaxi TrivediThe CTRI Center for Clinical Research has expanded its ultrasound imaging services and now offers a full range of sonography, including cardiac, vascular, general, gynecologic and small parts (i.e. thyroid, breast) ultrasound for clinical trials. Ultrasounds (or sonograms) use a computer and high-frequency sound waves to create images that are captured in real-time. They are convenient, painless, non-invasive, and yield quick results.

Minaxi Trivedi, a registered diagnostic medical sonographer, is available Wednesday through Friday, from 7 a.m. to 3 p.m., with some flexibility. She also is a registered cardiac sonographer, a registered vascular technologist, and a registered general ultrasound technologist. Trivedi uses a Philips PureWave HD15 ultrasound imaging system, with echocardiographic, vascular and general capabilities. The ultrasound unit is connected to a dedicated networked computer. All recordings are stored on a secure server at UC San Diego that is HIPAA compliant. Luis Castellanos, MD, provides medical expertise for the ultrasound service. Read more

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In This Issue

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Upcoming Seminars

CTRI Seminar Series

Dewleen Baker, MD, professor of psychiatry at UC San Diego, is scheduled to give a talk, “Seeking Risk and Resilience Factors for Development of PTSD: The Marine Resiliency Study,” on Tuesday, March 15. Read more

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Biostatistics Walk-in Consultation

Free walk-in biostatistics consultation is available every Wednesday from 1 P.M. to 5 P.M. in the CTRI offices at the East Campus Office Building. Read more

NIH National Center for Advancing Translational Sciences (NCATS)

CTRI

CTRI News and Funding Opportunities

Gary S. Firestein, MD
Director of CTRI

Patricia Wieser
Communications Director

Tracy Dezenzo
Graphic Designer

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