National Career Development Consortium for Excellence in Glycosciences

The National Career Development Consortium for Excellence in Glycosciences was created when the National Heart, Lung, and Blood Institute (NHLBI) awarded four career development grants to premier institutions, each of whom have created an independent local program to train the next generation of researchers in glycosciences - the study of complex carbohydrate molecules and their roles in human development and health.

The four centers form the National Consortium, sharing their resources, training opportunities and expertise across campuses.

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BLOODCENTER OF WISCONSIN PROGRAM FOR CAREER DEVELOPMENT IN GLYCOSCIENCES

The Center for Career Development BloodCenter Wisconsin (Translational Glycomics Program) is led by Karin Hoffmeister, MD (BCW/BRI), a trained cardiologist with expertise in translational research, glycobiology, hematopoiesis, thrombopoiesis and platelets. Other PIs on this grant are 1) Nancy Dahms, PhD (MCW), a trained glycobiologist with expertise in lysosome biogenesis and function, glycan-binding receptors and lysosomal storage disease; 2) Joseph Lau, PhD (RPCI), a trained glycobiologist with expertise in glycosyltransferase function, enzymology, inflammation, hematopoiesis, and immune responses, and 3) Umesh Desai, PhD (VCU), a trained medicinal chemist with expertise in computational chemistry, synthetic chemistry, and biophysical chemistry of glycosaminoglycans (GAGs).

Program PIs:

Nancy Dahms
Nancy M. Dahms
Professor
Medical College of Wisconsin
Lysosomal Storage Disease
Umesh Desai
Umesh R. Desai
Professor
Virginia Commonwealth University
GAGs / Proteomics
Karin Hoffmeister
Karin Hoffmeister
Director
Translational Glycomic Center
Glycomics / Hematology / Transfusion Medicine
Joseph Lau
Joseph T.Y. Lau
Professor
Roswell Park Division, State University of New York
Glycosylation / Hematology

HARVARD PROGRAM FOR CAREER DEVELOPMENT IN GLYCOSCIENCES

The Harvard Career Development Program's plan bridges two world-renowned medical centers affiliated with the Harvard Medical School – the Brigham & Women’s Hospital (BWH) and Beth Israel Deaconess Medical Center (BIDMC) – but anneals all the major research-intensive teaching hospitals affiliated with HMS (BWH, BIDMC, Boston Children’s Hospital (BCH), Massachusetts General Hospital (MGH), and the Dana-Farber Cancer Institute (DFCI), and, also, extends throughout all of Harvard University (including the Harvard University main campus in Cambridge, and the Schepens Eye Institute/Massachusetts Eye and Ear Infirmary that physically adjoins MGH). The BWH and BIDMC are physically next to each other, and the research labs of the Co-PIs are literally across the street (Blackfan Street) from each other: this intimate geography will promote seamless interactions among the Co-PIs and their respective labs and clinical care sites.

Program PIs:


Eliot Chaikof
Surgeon-in-Chief
Beth Israel Deaconess Medical
Glycobio. Structure-Function

Richard D. Cummings
Vice-Chair
Beth Israel Deaconess Medical
Cancer Glycobio. / Inflammation

Robert Sackstein
Sr. VP & Dean
Florida International University
Glycoengineering Cell Surfaces

JOHNS HOPKINS-CLEVELAND CLINIC PROGRAM FOR CAREER DEVELOPMENT IN GLYCOSCIENCES

“Immersive training in the Glycosciences” is a highly collaborative training program involving glycoscientists and clinical researchers at the Johns Hopkins University, the Complex Carbohydrate Research Center, and the Cleveland Clinic. The goal of our training program is to support the transition of scholars (physician scientists and post-doctoral fellows) into independent positions studying the role of glycans in heart, lung, blood, and sleep disorders. Scholar development will be supported by didactic and laboratory training, dual mentorship, professional development, and unique networking opportunities. Research areas include inflammatory diseases, cardiomyopathy, heart failure, ischemic heart disease, pulmonary and vascular injury, hypertension, obesity and diabetes, regenerative medicine, and blood disorders.

Program PIs:

Jeffrey D. Esko
Carol de la Motte
Interim Vice Chair
Cleveland Clinic, Lerner Research Institute
IBS/Hyaluronan
Gerald Hart
Gerald W. Hart

Professor
University of Georgia
Nutrient Regulation of Transcription
Vincent Hascall
Vincent C. Hascall
Section Head
Cleveland Clinic, Lerner Research Institute
Hyaluronan in Diabetic Pathologies
Ronald Midura
Ronald J. Midura
Sr. Researcher
Cleveland Clinic, Lerner Research Institute
Skeletal Phys. / Osteoporosis
Ronald Schnaar
Ronald Schnaar
Professor
Johns Hopkins School of Med.
Functions of Glycans
Natasha Zachara
Natasha E. Zachara
Associate Professor
Johns Hopkins School of Med.
Regulation of Cell Survival Decisions by O-GlcNAc

UC SAN DIEGO PROGRAM FOR CAREER DEVELOPMENT IN GLYCOSCIENCES

The UC San Diego Program for Career Development in Glycosciences is a cross-disciplinary program for postdoctoral (MD, MD/PhD, and PhD) scholars at UC San Diego.  Administered by the Glycobiology Research and Training center and comprising 19 mentors representing the UCSD Medical School, Biological and Physical Science Divisions, and the Schools of Pharmacy and Engineering, the program provides training opportunities in glycoscience across a broad range of areas of biomedical research. Our scholars are supported by a comprehensive didactic and practical glycoscience education program as well as the GlycoAnalytics and Mouse Phenotyping technical cores operated by the GRTC.

Program PIs:

Jeffrey D. Esko
Jeffrey D. Esko
Professor
U. of California, San Diego
Proteoglycans
Kamil Godula
Kamil Godula
Associate Professor
U. of California, San Diego
Glycoengineering
Ajit Varki
Ajit Varki
Professor
U. of California, San Diego
Sialic Acids