Introduction to Glycoscience

CHEM142 / CHEM242  |  Winter Quarter 2018  |  Tues, Thur 3:30-4:50 pm
Humanities and Social Sciences building (HSS) 2154
Co-Directors: Kamil Godula / Jeffrey Esko

Contact

Tracy Gilstrap
Education Coordinator
(858) 822-1378
tgilstrap@ucsd.edu

The primary aim is to provide an overview of fundamental facts, concepts, and methods in glycoscience. The course is structured around major themes in the field starting from basic understanding of structure and molecular interactions of carbohydrates, to the mechanisms of their biological functions in normal and disease states, to their applications in materials science and energy generation. This is a lecture course geared to introduce undergraduates and graduate students with limited prior exposure to the field, supported by selected readings and class notes.

Prerequisites: Organic Chemistry sequence and Biochemistry are required. Additionally, one course in either General Biology, Molecular Biology, or Cell Biology is strongly encouraged. Or, advance approval by instructors.

​Lecture #
​Date
​Title
​Instructor
​Lecture Notes
​1
​1/9/18
​Concepts of Glycoscience
​Godula/Esko
​2
1/11/18​​Diversity of Glycan Structures
​Godula
​3
1/16/18​​Properties of Glycans
​Godula
​4
​1/18/18
​Making Glycans from Scratch
​Godula

​5
​1/23/18
​Biosynthesis of Glycans
Godula​

​6
​1/25/18
​Glycan Interactions
​Godula
​7
​1/30/18
​Methods to Study Glycans
​Godula

​8
​2/1/18
O-Glycans
​Godula

​9
2/6/18​N-Glycans
​Esko

​10
​2/8/18
​Glycosaminoglycans
​Esko

11​
​2/13/18
​Glycolipids
​Esko


​2/15/18
​MIDTERM

​12
​2/20/18
​Plant Glycans
​Esko

​13
​2/22/18
​Where do glycans go to die?
​Esko

​14
​2/27/18
​The Evil Side of Glycans
​Esko

​15
​3/1/18
​Glycan-pathogen Interactions 
​Gordts

​16
​3/6/18
​Glycans in Evolution 
​Esko

​17
​3/8/18
​Glycans in Biotechnology
​Godula

​18
​3/13/18
​Glycans in Bioenergy and Materials
​Godula


​3/15/18
​Final project presentation I​
​​Godula/Esko


​3/20/18
Final project presentation I​I
​Godula/Esko


​3/22/18
​Final project presentation III
​Godula/Esko