MED 225/CHEM 237/BGGN 236
Offered every two years | First day of class: Tuesday, March 31, 2020
Tuesdays and Thursdays | 2:00pm - 3:20pm | Building BRF2, Room 2A03
Co-Directors: Jeffrey Esko and Kamil Godula
*Please go to Canvas for assigned reading, study questions, and presentation materials
*if you are off campus and would like access to the course materials please contact Tracy
Advanced elective for upper level undergraduates, graduate, and health sciences students who have taken Introduction to Glycoscience (Chem 142/242) and courses in cell biology or biochemistry. This course consists of discussions of classic papers leading to modern concepts in glycobiology, with the objective of exploring the structure, metabolism, and function of glycans in biological systems. Students should develop a sense of the history of the field, seminal discoveries, and how these discoveries led to changes in the way scientists think about glycans. Students will make 1-2 presentations in consultation with a faculty member.
This year the course will be divided up into five modules:
- Glycosylation Machinery and the Golgi
- The Heparin/Heparan Sulfate Code
- Mucosal Barriers
- Detective Work: The Story of Dystroglycan
- Flu and Glycan-Protein Interactions
is based on regular attendance and class participation.
Selected readings from primary literature and from the textbook Essentials of Glycobiology, 3rd Edition, Cold Spring Harbor Laboratory Press, New York.