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Fred Gage, PhD

Fred Gage, PhD

Adler Professor
Adjunct Professor - UC San Diego

Contact Information

Laboratory of Genetics
The Salk Institute for Biological Studies - LOGG
10010 N. Torrey Pines Rd.
La Jolla, CA 92037
Office Tel: 858-453-4100 x1012
Lab Tel: 858-453-4100 x1004
Fax: 858-597-0824

Fred H. Gage, a professor in the Laboratory of Genetics, concentrates on the adult central nervous system and unexpected plasticity and adaptability to environmental stimulation that remains throughout the life of all mammals. His work may lead to methods of replacing or enhancing brain and spinal cord tissues lost or damaged due to Neurodegenerative disease or trauma.

Gage’s lab showed that, contrary to accepted dogma, human beings are capable of growing new nerve cells throughout life. Small populations of immature nerve cells are found in the adult mammalian brain, a process called Neurogenesis. Gage is working to understand how these cells can be induced to become mature functioning nerve cells in the adult brain and spinal cord. They showed that environmental enrichment and physical exercise can enhance the growth of new brain cells and they are studying the underlying cellular and molecular mechanisms, that may be harnessed to repair the aged and damaged brain and spinal cord.