Past Colloquia - 2006

Monday, November 6

Randolph Hasting, M.D., Ph.D., Associate Professor, Dept. of Anesthesiology, UCSD School of Medicine

Bernard Wood, M.D., Ph.D., D.Sc., Henry R. Luce Professor of Human Origins, Center for the Advanced Study of Hominid Paleobiology, Dept. of Anthropology, George Washington University Adjunct Senior Scientist at the National Museum of Natural History, The Smithsonian Institution

Biomedical Magazine Review:  Bakre et al. Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor.  Nat Med 2002; 8:995-1003

Career Perspectives Speaker:  The reconstruction of human evolutionary history through developing and improving the ways we analyze the hominid fossil record; evolution of human growth and development.

Wednesday, October 25

Roland Blantz, M.D., Professor & Head, Dept. of Medicine, Div. of Nephrology-Hypertension

Peter Agre, M.D., Nobel Prize, Chemistry 2003, Vice Chancellor for Science & Technology, Professor of Cell Biology, Duke University Medical Center

Biomedical Magazine Review:  Habashi JP et al. Losartan, an AT1 Antagonist, Prevents Aortic Aneurysm in a Mouse Model of Marfan Syndrome.   Science 2006; 312:117-121.

Career Perspectives Speaker:  Molecular and cellular analysis of the transport of water across cell membranes in health and disease; aquaporins.

Wednesday, September 20

Ajit Varki, M.D., Distinguished Professor of Medicine and Cellular & Molecular Medicine, Associate Dean for Physician-Scientist Training

Judith Swain, M.D., Founding Dean for Translational Research and Professor of Medicine

Edward Holmes, M.D., Vice-Chancellor for Health Sciences, Dean, UCSD School of Medicine, Exe. Dpty. Chairman-Elect, Clinical Translational Sciences, Biomedical Research Council and Lien Ying Chow Professor of Medicine, Yong Loo Lin School of Medicine, National University of Singapore

Biomedical Magazine Review:  "Cytokine Storm in a Phase 1 Trial of the Anti-CD28 Monoclonal Antibody TGN1412," Suntharalingam et al. NEJM 2006:355

Career Perspectives Speaker:  Genetic basis of cardiovascular development and disease.  Role of growth factors in angiogenesis.  Research program development and interdisciplinary collaboration across the continuum of discovery, development and patient care.

Closing Comments

Monday, August 21

Maripat Corr, M.D., Associate Professor of Medicine, Div. of Rheumatology

Patricia Thistlethwaite, M.D., Ph.D., Associate Professor of Surgery, Div. of Cardiovascular & Thoracic Surgery

Nissi Varki, M.D., Professor of Pathology & Medicine Cancer Biology Program

Women in Medicine

Monday, July 31

Christine Moutier, M.D., Asst. Clinical Professor, Dept. of Psychiatry, Asst. Dean, Students & Curricular Affairs

Robert Hertzka, M.D., President, California Medical Association (CMA), Professor, Dept. of Anesthesiology

Bryan Liang, JD, M.D., Ph.D., Professor of Law, California Western School of Law, Exec. Dir., Institute of Health Law Studies

Sanjay Nigam, M.D., Professor of Pediatrics, Medicine, and Cellular & Molecular Medicine, Author, The Snake Charmer and The Transplanted Man

Alternatives to the Scientist Pathway

Career Perspectives of a Physician-Scientist-Writer

Monday, May 22

Douglas Richman, M.D., Professor of Pathology & Medicine, F.S. Riford Chair in AIDS Research, Dir., UCSD Center for AIDS Research

Helen Ranney, M.D., Professor and Chair Emeritus, Dept. of Medicine

Biomedical Magazine Review:  Mattapallil JJ et al.  Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection. Nature 2005; 434:1080-1.

Career Perspectives Speaker:  Structure and function of hemoglobin, hemoglobinopathies, biochemistry and genetics underlying sickle cell anemia

Monday, April 24

Ravindra Mehta, MBBS, M.D., Professor of Medicine, Div. of Nephrology and Hypertension, Assoc. Chair for Clinical Affairs

Chuck Stevens, M.D., Ph.D., Professor and Vincent J. Coates Chair, Molecular Neurobiology, Salk

Biomedical Magazine Review:  Mishra J et al.  Neutrophil gelatinase-Assoc.d lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet 2005; 365:1231-8.

Career Perspectives Speaker:  Mechanisms responsible for neuronal synaptic transmission. Function of hippocampal synapses; mechanisms of synaptic plasticity and the relevance of plasticity to neuronal computations.  Molecular basis of neurotransmitter release.

Monday, March 27

Anthony Wynshaw-Boris, M.D., Ph.D., Professor of Pediatrics & Medicine, Dir., UCSD Center for Human Genetics & Genomics

Shu Chien, M.D., Ph.D., Professor of Bioengineering & Medicine, Dir., Whitaker Inst. of Biomedical Engineering

Biomedical Magazine Review:  Iafrate et al. "Detection of large scale variation in the human genome." Nat Genet. 2004; 36:949-51.

Career Perspectives Speaker:  Effects of mechanical forces on gene expression and signal transduction.  Role of biomechanical factors in atherosclerosis. Molecular, cellular, and tissue bioengineering.

Tuesday, February 28

Gary Firestein, M.D., Professor of Medicine, Chief, Div. of Rheumatology, Allergy & Immunology, Exec. Dir., UCSD Center for Innovative Therapy

Sydney Brenner, M.D., Distinguished Professor, Salk Institute for Biological Studies, Nobel Laureate in Medicine 2002

Biomedical Magazine Review:  Camps et al. "Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis." Nat Med. 2005; 11:936-43.

Career Perspectives Speaker:  Genetics and molecular biology; discovery of the existence of mRNA and demonstration of how amino acid order is established in proteins; pioneering work with the roundworm C. elegans as a model of nerve cell function, aging and apoptosis.

Monday, January 23

Sanford Shattil, M.D., Professor of Medicine, Editor-in-Chief, Blood

Pedro Cuatrecasas, M.D., Adjunct Professor of Pharmacology & Medicine, President, Retired, Parke Davis/Warner Lambert Pharmaceutical Research Div.

Special Presentation:  "An Editor's Perspective:  How to Write a Paper for a Scientific Journal in 2006"

Career Perspectives Speaker:  Affinity chromatography, membrane  receptors, signal transduction for insulin and other growth factors; Discovery and development of drugs for diabetes, HIV, bacterial infections, epilepsy, cancer, Alzheimer's and depression.